Study of Multimode Extrinsic Fabry-Perot Interferometric Fiber Optic Sensor on Biosensing

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dc.contributor.authorZhao, Xinen
dc.contributor.committeechairWang, Anboen
dc.contributor.committeememberPickrell, Gary R.en
dc.contributor.committeememberCooper, Kristie L.en
dc.contributor.departmentElectrical and Computer Engineeringen
dc.date.accessioned2014-03-14T20:43:26Zen
dc.date.adate2007-03-07en
dc.date.available2014-03-14T20:43:26Zen
dc.date.issued2006-08-01en
dc.date.rdate2012-04-06en
dc.date.sdate2006-08-14en
dc.description.abstractThe electrostatic self-assembly (ESA) method presents an effective application in the field of biosensing due to the uniform nanoscale structure. In previous research, a single mode fiber (SMF) sensor system had been investigated for the thin-film measurement due to the high fringe visibility. However, compared with a SMF sensor system, a multimode fiber (MMF) sensor system is lower-cost and has larger sensing area (the fiber core), providing the potential for higher sensing efficiency. In this thesis, a multimode fiber-optic sensor has been developed based on extrinsic Fabry-Perot interferometry (EFPI) for the measurement of optical thickness in self-assembled thin film layers as well as for the immunosensing test. The sensor was fabricated by connecting a multimode fiber (MMF) and a silica wafer. A Fabry-Perot cavity was formed by the reflections from the two interfaces of the wafer. The negatively charged silica wafer could be used as the substrate for the thin film immobilization scheme. The sensor is incorporated into the white-light interferometric system. By monitoring the optical cavity length increment, the self-assembled thin film thickness was measured; the immunoreaction between immunoglobulin G (IgG) and anti-IgG was investigated.en
dc.description.degreeMaster of Scienceen
dc.identifier.otheretd-08142006-235542en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-08142006-235542/en
dc.identifier.urihttp://hdl.handle.net/10919/34534en
dc.publisherVirginia Techen
dc.relation.haspartThesis_Xin_Zhao.pdfen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectElectrostatic self-assembly (ESA)en
dc.subjectFabry-Peroten
dc.subjectMultimode Fiber Optic Sensorsen
dc.subjectWhite-light Interferometryen
dc.subjectBiosensoren
dc.titleStudy of Multimode Extrinsic Fabry-Perot Interferometric Fiber Optic Sensor on Biosensingen
dc.typeThesisen
thesis.degree.disciplineElectrical and Computer Engineeringen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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