An empirical constitutive equation for anti-coagulated human blood

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dc.contributor.authorWalburn, Frederick Jamesen
dc.contributor.departmentEngineering Science and Mechanicsen
dc.date.accessioned2014-03-14T20:47:15Zen
dc.date.adate2008-10-30en
dc.date.available2014-03-14T20:47:15Zen
dc.date.issued1975en
dc.date.rdate2008-10-30en
dc.date.sdate2008-10-30en
dc.description.abstractA constitutive equation for whole human blood was developed using a power law functional form. This power law equation contains two parameters, the consistency index and the non-Newtonian index for the fluid. Viscometric data, utilizing a cone and plate viscometer, were obtained from anticoagulated blood samples of known hematocrit levels and chemical compositions. A multiple regression technique with apparent viscosity as the dependent variable was used to determine the consistency index and the non-Newtonian index. A model including only the shear rate as the independent variable was found to be lacking any substantial degree of significance. When hematocrit was added as an independent variable, the degree of fit increased considerably. Of the chemical variables examined, the least significant, as far as effects on viscosity is concerned, were the plasma lipids. The proteins, fibrinogen and globulin were found to have a much greater effect on viscosity than the protein, albumin. The best constitutive equation involving the chemical composition of blood was found to include the shear rate, the hematocrit level, and a variable which is the sum of fibrinogen and globulin. This model produced a statistically significant increase in the correlation between experimental and theoretical data compared with the best two variable model.en
dc.description.degreeMaster of Scienceen
dc.format.extentvii, 91 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-10302008-120539en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-10302008-120539/en
dc.identifier.urihttp://hdl.handle.net/10919/35540en
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V855_1975.W338.pdfen
dc.relation.isformatofOCLC# 39069869en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V855 1975.W338en
dc.titleAn empirical constitutive equation for anti-coagulated human blooden
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineEngineering Science and Mechanicsen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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