Use of Glucose Monitoring Systems in Horses

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dc.contributor.authorMalik, Caitlin Elyseen
dc.contributor.committeechairMcKenzie, Harold C.en
dc.contributor.committeememberWong, David Michaelen
dc.contributor.committeememberWilson, Katherine E.en
dc.contributor.departmentBiomedical and Veterinary Sciencesen
dc.date.accessioned2022-09-01T08:00:20Zen
dc.date.available2022-09-01T08:00:20Zen
dc.date.issued2022-08-31en
dc.description.abstractTraditional methods of blood glucose monitoring involve obtaining samples for measurement via laboratory methodology or point of care devices and require invasive collection techniques such as capillary stick, venipuncture, or the placement of intravenous catheters. Limitations of traditional methods include the limited information provided by intermittent testing and the stress associated with restraint and discomfort experienced by patients. The snapshot nature of the provided information restricts a clinician's ability to truly monitor trends in glucose concentrations over an extended period of time, influencing clinical decision making. The stress of invasive sampling can cause stress hyperglycemia in many veterinary species, complicating interpretation. Continuous interstitial glucose monitoring technology is widely used in the human medical field due to the expansive information provided in a minimally invasive manner. In recent years, the device technology has advanced and cost has improved, prompting application of these devices into the veterinary sector. Studies have shown good agreement between newer glucose monitoring systems and traditional methods in small animal patients with diabetes mellitus, allowing veterinarians to obtain comprehensive glucose data with minimal stress and discomfort to the patient. However, information regarding the use of this new technology in equine medicine is limited. The following study describes the evaluation of two widely available glucose monitoring systems, the Dexcom G6 and the FreeStyle Libre, in healthy adult horses.en
dc.description.abstractgeneralMonitoring of glucose concentrations is essential for the diagnosis and monitoring of a variety of disorders within equine medicine. Traditional methods of obtaining samples for testing include capillary stick, venipuncture, or the placement of intravenous catheters, which can cause stress and discomfort to equine patients. The information obtained by this testing methodology only allows for intermittent assessment of glucose concentrations, limiting the amount of information available for clinicians to make clinical decisions. The use of continuous glucose monitoring systems in the human medical field have allowed clinicians to obtain continuous or near-continuous glucose concentrations, improving interpretation. These devices have nearly eliminated the need for blood sampling for glucose concentrations, instead relying on interstitial glucose concentrations which have been shown to compare favorably to blood concentrations. Studies in small animal veterinary species, such as dogs and cats, have shown good agreement between newer glucose monitoring systems and traditional methods in small animal patients with diabetes mellitus, allowing veterinarians to obtain comprehensive glucose data with minimal stress and discomfort to the patient. However, information regarding the use of this new technology in horses is limited. The study described in the manuscript following evaluates the use of two widely available glucose monitoring systems, the Dexcom G6 and the FreeStyle Libre, in healthy adult horse.en
dc.description.degreeMaster of Scienceen
dc.format.mediumETDen
dc.identifier.othervt_gsexam:35315en
dc.identifier.urihttp://hdl.handle.net/10919/111682en
dc.language.isoenen
dc.publisherVirginia Techen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectcontinuous glucose monitoringen
dc.subjectequine medicineen
dc.titleUse of Glucose Monitoring Systems in Horsesen
dc.typeThesisen
thesis.degree.disciplineBiomedical and Veterinary Sciencesen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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