Inhibition of Bacillus subtilis respiration on glucose, formate and succinate by certain anesthetic agents

dc.contributor.authorNutting, Leighton Adamsen
dc.contributor.departmentBacteriologyen
dc.date.accessioned2024-05-08T00:07:46Zen
dc.date.available2024-05-08T00:07:46Zen
dc.date.issued1948en
dc.description.abstractThe non-proliferating or “resting” cell technic and the Werburg respirometer have been employed to study the respiration of <i>Bacillus subtilis</i> Koch-Novy with glucose, formate and succinate as substrates. The enzymatic oxidation of these substrates in the presence of cyanide, urethane, chloral hydrate, chloroform and other have been investigated and the effects of these agents over a range of concentrations have been noted. Graphs have been prepared for comparison of the oxygen consumption and carbon dioxide liberation values for <i>Bacillus subtilis</i> Koch-Novy in the presence and absence of the various inhibitory agents. Differences between the oxidation of succinate by bacteria and by mammalian brain tissue have been pointed out. Information concerning the oxidations of brain tissue was obtained from the previous work of Quastel et al and Grieg (11, 23, 24). Gaseous exchange which suggest some sort of metabolic action by <i>Bacillus subtilis</i> Koch-Novy on chloretone has been noted. The author has expressed an opinion regarding the advisability of employing members of the genus <i>Bacillus</i> for studies concerning the mode of section of anesthetic agents.en
dc.description.degreeM.S.en
dc.format.extent[10], 125 leavesen
dc.format.mimetypeapplication/pdfen
dc.identifier.urihttps://hdl.handle.net/10919/118857en
dc.language.isoenen
dc.publisherVirginia Polytechnic Instituteen
dc.relation.isformatofOCLC# 29817868en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V855 1948.N877en
dc.subject.lcshAnestheticsen
dc.subject.lcshBacillus subtilisen
dc.subject.lcshCell respirationen
dc.titleInhibition of Bacillus subtilis respiration on glucose, formate and succinate by certain anesthetic agentsen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineBacteriologyen
thesis.degree.grantorVirginia Polytechnic Instituteen
thesis.degree.levelmastersen
thesis.degree.nameM.S.en

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