The role of gut microbiota in different murine models of systemic lupus erythematosus

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dc.contributor.authorLu, Ranen
dc.contributor.authorLuo, Xin M.en
dc.date.accessioned2024-12-19T15:29:39Zen
dc.date.available2024-12-19T15:29:39Zen
dc.date.issued2024-07-16en
dc.description.abstractSystemic lupus erythematosus (SLE) is an autoimmune disorder characterized by immune system dysfunction that can lead to serious health issues and mortality. Recent investigations highlight the role of gut microbiota alterations in modulating inflammation and disease severity in SLE. This review specifically summaries the variations in gut microbiota composition across various murine models of lupus. By focusing on these differences, we aim to elucidate the intricate relationship between gut microbiota dysbiosis and the development and progression of SLE in preclinical settings.en
dc.description.versionPublished versionen
dc.format.extent14 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifierARTN 2378876 (Article number)en
dc.identifier.doihttps://doi.org/10.1080/08916934.2024.2378876en
dc.identifier.eissn1607-842Xen
dc.identifier.issn0891-6934en
dc.identifier.issue1en
dc.identifier.orcidLuo, Xin [0000-0002-2809-5836]en
dc.identifier.pmid39014962en
dc.identifier.urihttps://hdl.handle.net/10919/123836en
dc.identifier.volume57en
dc.language.isoenen
dc.publisherTaylor & Francisen
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/39014962en
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectLupusen
dc.subjectSLEen
dc.subjectgut microbiotaen
dc.subjectmouse modelsen
dc.subjectleaky guten
dc.subjectmolecular mimicryen
dc.subjectimmune dysregulationen
dc.subject.meshAnimalsen
dc.subject.meshHumansen
dc.subject.meshMiceen
dc.subject.meshLupus Erythematosus, Systemicen
dc.subject.meshDisease Models, Animalen
dc.subject.meshDysbiosisen
dc.subject.meshGastrointestinal Microbiomeen
dc.titleThe role of gut microbiota in different murine models of systemic lupus erythematosusen
dc.title.serialAutoimmunityen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherJournalen
pubs.organisational-groupVirginia Techen
pubs.organisational-groupVirginia Tech/Veterinary Medicineen
pubs.organisational-groupVirginia Tech/Veterinary Medicine/Biomedical Sciences and Pathobiologyen
pubs.organisational-groupVirginia Tech/Faculty of Health Sciencesen
pubs.organisational-groupVirginia Tech/All T&R Facultyen
pubs.organisational-groupVirginia Tech/Veterinary Medicine/CVM T&R Facultyen

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