New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis

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dc.contributor.authorZhang, Leien
dc.contributor.authorYuan, Junen
dc.contributor.authorXu, Y.en
dc.contributor.authorZhang, Y. H. Percivalen
dc.contributor.authorQian, Xuhongen
dc.contributor.departmentBiological Systems Engineeringen
dc.date.accessioned2016-12-22T18:17:31Zen
dc.date.available2016-12-22T18:17:31Zen
dc.date.issued2016-01-01en
dc.description.abstractA new artificial fluoro-cofactor was developed for the replacement of natural cofactors NAD(P), exhibiting a high hydride transfer ability. More importantly, we established a new and fast screening method for the evaluation of the properties of artificial cofactors based on the fluorescence assay and visible color change.en
dc.description.versionPublished versionen
dc.format.extent6471 - 6474 (4) page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1039/c6cc02002jen
dc.identifier.issn1359-7345en
dc.identifier.issue38en
dc.identifier.urihttp://hdl.handle.net/10919/73802en
dc.identifier.volume52en
dc.language.isoenen
dc.publisherRoyal Society of Chemistryen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000375624100029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectChemistry, Multidisciplinaryen
dc.subjectChemistryen
dc.subjectBIOMIMETIC ASYMMETRIC HYDROGENATIONen
dc.subject1,4-NADH DERIVATIVESen
dc.subjectBIOORGANOMETALLIC CHEMISTRYen
dc.subjectREGIOSELECTIVE REDUCTIONen
dc.subjectMEDICINAL CHEMISTRYen
dc.subjectMECHANISTIC ASPECTSen
dc.subjectNAD(P)H OXIDASEen
dc.subjectNAD(+) MODELSen
dc.subjectREGENERATIONen
dc.subjectNICOTINAMIDEen
dc.titleNew artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysisen
dc.title.serialChemical Communicationsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciencesen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Biological Systems Engineeringen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Facultyen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Faculty of Health Sciencesen

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