Influence of molybdenum and sulfate supplementation and withdrawal of diets containing high copper broiler litter on tissue copper levels
| dc.contributor.author | Olson, Kristi Jo | en |
| dc.contributor.department | Animal Science (Ruminant Nutrition) | en |
| dc.date.accessioned | 2019-01-31T18:27:30Z | en |
| dc.date.available | 2019-01-31T18:27:30Z | en |
| dc.date.issued | 1982 | en |
| dc.description.abstract | Thirty-six mature, nongestating, crossbred ewes were randomly allotted to three diets: basal (6 ewes); 50% basal and 50% broiler litter (24 ewes), and 50% basal and 50% broiler litter with the addition of 25 ppm molybdenum (Mo) and 5 g sulfate/kg feed. The 24 litter fed ewes were allotted to withdrawal times of 0-, 30-, 60- and 120-d. The control (basal) diet contained and the deepstacked broiler litter contained 8 and 257 ppm Cu, dry basis, respectively. The ewes were fed the diets for 140-d at which time the control, the six litter-fed ewes with 0-d withdrawal and the Mo and SO₄ supplemented ewes were slaughtered. Liver samples were obtained from these ewes by biopsy initially and at 40-, 80-, and 120-d of the trial. At slaughter liver, kidney, muscle and duodenum samples were taken. Liver Cu content was increased (P<.01) by feeding broiler litter (404 vs 1543 ppm, dry basis). Liver Cu (962 ppm) accumulation and serum Cu were depressed (P<.05) by supplementing litter containing diets with Mo and SO₄. Zinc levels of the liver and Zn and Cu levels of the kidney and muscle were not affected by additional Mo and SO₄. Duodenum Cu and Zn levels reflected the dietary metal content. During the withdrawal period liver and duodenum Cu levels were not lowered (P>.05). A linear increase (P<.001) in SGOT activity was observed with time throughout the withdrawal period, suggesting possible liver damage. Serum Cu decreased at 30-d and increased thereafter (quadratic effect, P<.05). This observation coupled with increases in muscle and kidney Cu (P<.05) indicated an apparent redistribution of Cu stores. Metallothionein (MT) increased 12-fold above control values in the litter-fed ewes (P<.05) and tended to decrease during the withdrawal period. Therefore, it appears that supplementing Mo and SO₄ to a diet containing high Cu broiler litter may reduce the accumulation of hepatic Cu. Liver Cu stores will not be dissipated upon withdrawal of the high Cu litter from the diet. | en |
| dc.description.degree | Master of Science | en |
| dc.format.extent | vii, 64, [2] leaves | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.uri | http://hdl.handle.net/10919/87245 | en |
| dc.language.iso | en_US | en |
| dc.publisher | Virginia Polytechnic Institute and State University | en |
| dc.relation.isformatof | OCLC# 9375591 | en |
| dc.rights | In Copyright | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en |
| dc.subject.lcc | LD5655.V855 1982.O476 | en |
| dc.subject.lcsh | Molybdenum in animal nutrition | en |
| dc.subject.lcsh | Ewes -- Feeding and feeds | en |
| dc.title | Influence of molybdenum and sulfate supplementation and withdrawal of diets containing high copper broiler litter on tissue copper levels | en |
| dc.type | Thesis | en |
| dc.type.dcmitype | Text | en |
| thesis.degree.discipline | Animal Science (Ruminant Nutrition) | en |
| thesis.degree.grantor | Virginia Polytechnic Institute and State University | en |
| thesis.degree.level | masters | en |
| thesis.degree.name | Master of Science | en |
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