Approaches Used to Construct Antibiograms for Dogs in a Veterinary Teaching Hospital in the United States
| dc.contributor.author | Ekakoro, John E. | en |
| dc.contributor.author | Guptill, Lynn | en |
| dc.contributor.author | Hendrix, Kenitra | en |
| dc.contributor.author | Anderson, Melinda | en |
| dc.contributor.author | Ruple, Audrey | en |
| dc.date.accessioned | 2023-06-27T17:26:53Z | en |
| dc.date.available | 2023-06-27T17:26:53Z | en |
| dc.date.issued | 2023-06-09 | en |
| dc.date.updated | 2023-06-27T13:22:07Z | en |
| dc.description.abstract | Non-judicious antimicrobial use (AMU) is a major driver of antimicrobial resistance (AMR). In human hospitals, cumulative antibiograms are often used by clinicians to evaluate local susceptibility rates and to select the most appropriate empiric therapy with the aim of minimizing inappropriate AMU. However, the use of cumulative antibiograms to guide empiric antimicrobial therapy in veterinary hospitals in the United States is limited, and there are no specific guidelines or standardized methods available for the construction of antibiograms in veterinary clinical settings. The objective of this methods article is to describe the approaches that were used to construct antibiograms from clinical samples collected from dogs seen at a veterinary teaching hospital. Laboratory data for 563 dogs for the period from 1 January 2015 to 31 December 2015 was utilized. We used the Clinical and Laboratory Standards Institute (CLSI) guidelines for use in the construction of the antibiograms in human healthcare settings as the basis for the veterinary antibiograms. One general antibiogram and antibiograms stratified by hospital section, the anatomic region of sample collection/by sample type, were created and the challenges encountered in preparing these antibiograms were highlighted. The approaches described could be useful in guiding veterinary antibiogram development for empiric therapy. | en |
| dc.description.version | Published version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Ekakoro, J.E.; Guptill, L.; Hendrix, K.; Anderson, M.; Ruple, A. Approaches Used to Construct Antibiograms for Dogs in a Veterinary Teaching Hospital in the United States. Antibiotics 2023, 12, 1034. | en |
| dc.identifier.doi | https://doi.org/10.3390/antibiotics12061034 | en |
| dc.identifier.uri | http://hdl.handle.net/10919/115534 | en |
| dc.language.iso | en | en |
| dc.publisher | MDPI | en |
| dc.rights | Creative Commons Attribution 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en |
| dc.subject | antimicrobial resistance | en |
| dc.subject | canine patients | en |
| dc.subject | empiric antimicrobial therapy | en |
| dc.subject | Gram-negative bacteria | en |
| dc.subject | Gram-positive bacteria | en |
| dc.subject | veterinary antibiograms | en |
| dc.title | Approaches Used to Construct Antibiograms for Dogs in a Veterinary Teaching Hospital in the United States | en |
| dc.title.serial | Antibiotics | en |
| dc.type | Article - Refereed | en |
| dc.type.dcmitype | Text | en |