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Occlusion of the Internal Carotid Artery of Horses: Evaluation of a Technique Designed to Prevent Epistaxis Caused by Guttural Pouch Mycosis

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dc.contributor.authorCheramie, Hoyt Stephenen
dc.contributor.committeechairPleasant, R. Scotten
dc.contributor.committeememberCarrig, Colin B.en
dc.contributor.committeememberRobertson, John L.en
dc.contributor.committeememberMoll, H. Daviden
dc.contributor.departmentVeterinary Medical Sciencesen
dc.date.accessioned2014-03-14T20:49:34Zen
dc.date.adate1998-12-16en
dc.date.available2014-03-14T20:49:34Zen
dc.date.issued1998-06-19en
dc.date.rdate2012-06-22en
dc.date.sdate1998-12-14en
dc.description.abstractIn six, healthy, adult horses, the origin of the left internal carotid artery was isolated via a modified hyovertebrotomy approach. Normograde blood flow was occluded by placement of a tourniquet on the artery near its origin. Lumenal access was gained through placement of a distally directed introducer sheath and retrograde blood flow from the cerebral arterial circle was confirmed. An 8.5 mm diameter detachable latex balloon loaded onto a carrier catheter and placed within a guiding catheter was introduced into the internal carotid artery through the introducer sheath and advanced to the target occlusion site (the proximal curve of the sigmoid flexure of the internal carotid artery). The balloon was inflated with 0.5 ml of a radiopaque solution. Correct placement and inflation of the balloon were confirmed by intraoperative radiography. The balloon was then released and the guiding and carrier catheters withdrawn. Immediate embolization of the distal internal carotid artery was determined by lack of retrograde blood flow through the introducer sheath. The introducer sheath was withdrawn from the vessel and the proximal tourniquet was replaced with two ligatures. Horses were euthanized on day 30 and detailed gross and histopathologic examinations were performed. The balloons were easily placed into the target site and produced immediate occlusion of retrograde flow from the cerebral arterial circle. All balloons remained inflated in their original position throughout the study period. Mature thrombus formation and absence of clinically significant inflammation were consistent findings in all occluded internal carotid arteries at gross necropsy and histologic examination.en
dc.description.degreeMaster of Scienceen
dc.identifier.otheretd-121498-140221en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-121498-140221/en
dc.identifier.urihttp://hdl.handle.net/10919/36141en
dc.publisherVirginia Techen
dc.relation.haspartCheramieETD.pdfen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectEquineen
dc.subjectFungal Infectionen
dc.subjectEmbolizationen
dc.titleOcclusion of the Internal Carotid Artery of Horses: Evaluation of a Technique Designed to Prevent Epistaxis Caused by Guttural Pouch Mycosisen
dc.typeThesisen
thesis.degree.disciplineVeterinary Medical Sciencesen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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