The effect of protein intake on the excretion of vitamin B₆, 4-pyridoxic acid, and xanthurenic acid in preadolescent boys

dc.contributor.authorJohnson, Frances Somervellen
dc.contributor.departmentHuman Nutrition and Foodsen
dc.date.accessioned2024-03-12T20:23:17Zen
dc.date.available2024-03-12T20:23:17Zen
dc.date.issued1975en
dc.description.abstractThe effect of protein intake on vitamin B<sub>6</sub> status was investigated in preadolescent boys. Twelve subjects rotated through a diet sequence containing daily intakes of 1.15 mg vitamin B<sub>6</sub> and 29, 54, or 84 rim protein. Total vitamin B<sub>6</sub> and 4-pyridoxic acid were determined in urine composites from the last 5 days of a 10-day experimental period. Xanthurenic acid, following a 2 gm L-tryptophan dose, was assayed from urine collected on the last day of each experimental period. There were significant differences found between period vitamin B<sub>6</sub> intakes in diets containing varying levels of dietary protein. However, vitamin B<sub>6</sub>, 4-pyridoxic acid, and xanthurenic acid excretion was not significantly different between subjects consuming 29, 54, or 84 gm protein. The excretion of these metabolites varied from period to period for each child. Mean group data indicated that consumption of the low protein diet resulted in highest excretion of vitamin B<sub>6</sub> and 4-pyridoxic acid and lowest excretion of xanthurenic acid. Highest excretion of xanthurenic acid and lowest vitamin B<sub>6</sub> excretion were observed in response to the high protein diet. Although these excretion patterns suggested an effect of protein intake, the differences between excretion of these metabolites on the basis of protein level were not significant. A daily intake of approximately 1.15 mg vitamin B<sub>6</sub> was adequate for maintenance of proper vitamin 86 nutriture for subjects consuming low, medium and high protein diets. The possible cause for the variation between groups due to the diet rotation sequence is discussed. Since the vitamin B<sub>6</sub> requirement - protein intake relationship has been exclusively studied in adults, suggestions for further research on this problem with preadolescent children are recommended.en
dc.description.degreeM.S.en
dc.format.extentvi, 66 leaveen
dc.format.mimetypeapplication/pdfen
dc.identifier.urihttps://hdl.handle.net/10919/118333en
dc.language.isoenen
dc.publisherVirginia Polytechnic Institute and State Universityen
dc.relation.isformatofOCLC# 39011063en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V855 1975.J635en
dc.titleThe effect of protein intake on the excretion of vitamin B₆, 4-pyridoxic acid, and xanthurenic acid in preadolescent boysen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineHuman Nutrition and Foodsen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameM.S.en

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