Robust and Transparent Silver Oxide Coating Fabricated at Room Temperature Kills Clostridioides difficile Spores, MRSA, and Pseudomonas aeruginosa
| dc.contributor.author | Hosseini, Mohsen | en |
| dc.contributor.author | Huang, Jinge | en |
| dc.contributor.author | Williams, Myra D. | en |
| dc.contributor.author | Gonzalez, Gerardo Alexander | en |
| dc.contributor.author | Jiang, Xiuping | en |
| dc.contributor.author | Falkinham, Joseph O. | en |
| dc.contributor.author | Ducker, William A. | en |
| dc.date.accessioned | 2024-02-01T14:32:10Z | en |
| dc.date.available | 2024-02-01T14:32:10Z | en |
| dc.date.issued | 2023-12-31 | en |
| dc.date.updated | 2024-01-26T14:10:29Z | en |
| dc.description.abstract | Antimicrobial coatings can inhibit the transmission of infectious diseases when they provide a quick kill that is achieved long after the coating application. Here, we describe the fabrication and testing of a glass coating containing Ag<sub>2</sub>O microparticles that was prepared from sodium silicate at room temperature. The half-lives of both methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) and <i>Pseudomonas aeruginosa</i> on this coating are only 2–4 min. The half-life of <i>Clostridioides difficile</i> spores is about 9–12 min, which is extremely short for a spore. Additional tests on MRSA demonstrate that the coating retains its antimicrobial activity after abrasion and that an increased loading of Ag<sub>2</sub>O leads to a shorter half-life. This coating combines the properties of optical transparency, robustness, fast kill, and room temperature preparation that are highly desirable for an antimicrobial coating. | en |
| dc.description.version | Published version | en |
| dc.format.mimetype | application/pdf | en |
| dc.identifier.citation | Hosseini, M.; Huang, J.; Williams, M.D.; Gonzalez, G.A.; Jiang, X.; Falkinham, J.O., III; Ducker, W.A. Robust and Transparent Silver Oxide Coating Fabricated at Room Temperature Kills Clostridioides difficile Spores, MRSA, and Pseudomonas aeruginosa. Microorganisms 2023, 12, 83. | en |
| dc.identifier.doi | https://doi.org/10.3390/microorganisms12010083 | en |
| dc.identifier.uri | https://hdl.handle.net/10919/117798 | en |
| dc.language.iso | en | en |
| dc.publisher | MDPI | en |
| dc.rights | Creative Commons Attribution 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | en |
| dc.title | Robust and Transparent Silver Oxide Coating Fabricated at Room Temperature Kills Clostridioides difficile Spores, MRSA, and Pseudomonas aeruginosa | en |
| dc.title.serial | Microorganisms | en |
| dc.type | Article - Refereed | en |
| dc.type.dcmitype | Text | en |