Nanomechanical motion of Escherichia coli adhered to a surface

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dc.contributor.authorLissandrello, C.en
dc.contributor.authorInci, F.en
dc.contributor.authorFrancom, M.en
dc.contributor.authorPaul, Mark R.en
dc.contributor.authorDemirci, U.en
dc.contributor.authorEkinci, K. L.en
dc.date.accessioned2024-10-09T13:55:28Zen
dc.date.available2024-10-09T13:55:28Zen
dc.date.issued2014-09-16en
dc.description.abstractNanomechanical motion of bacteria adhered to a chemically functionalized silicon surface is studied by means of a microcantilever. A non-specific binding agent is used to attach Escherichia coli (E. coli) to the surface of a silicon microcantilever. The microcantilever is kept in a liquid medium, and its nanomechanical fluctuations are monitored using an optical displacement transducer. The motion of the bacteria couples efficiently to the microcantilever well below its resonance frequency, causing a measurable increase in the microcantilever fluctuations. In the time domain, the fluctuations exhibit large-amplitude low-frequency oscillations. In corresponding frequency-domain measurements, it is observed that the mechanical energy is focused at low frequencies with a 1/fα-type power law. A basic physical model is used for explaining the observed spectral distribution of the mechanical energy. These results lay the groundwork for understanding the motion of microorganisms adhered to surfaces and for developing micromechanical sensors for bacteria.en
dc.description.versionPublished versionen
dc.format.extent5 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifierARTN 113701 (Article number)en
dc.identifier.doihttps://doi.org/10.1063/1.4895132en
dc.identifier.eissn1077-3118en
dc.identifier.issn0003-6951en
dc.identifier.issue11en
dc.identifier.orcidPaul, Mark [0000-0002-0701-1955]en
dc.identifier.other1.4895132 (PII)en
dc.identifier.pmid25316924en
dc.identifier.urihttps://hdl.handle.net/10919/121313en
dc.identifier.volume105en
dc.language.isoenen
dc.publisherAmerican Institute of Physicsen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342995800101&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.relation.urihttp://dx.doi.org/10.1063/1.4895132en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.titleNanomechanical motion of Escherichia coli adhered to a surfaceen
dc.title.serialApplied Physics Lettersen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
dcterms.dateAccepted2014-08-28en
pubs.organisational-groupVirginia Techen
pubs.organisational-groupVirginia Tech/Engineeringen
pubs.organisational-groupVirginia Tech/Engineering/Mechanical Engineeringen
pubs.organisational-groupVirginia Tech/All T&R Facultyen
pubs.organisational-groupVirginia Tech/Engineering/COE T&R Facultyen

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