A naturally derived biomaterial formulation for improved menstrual care

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dc.contributor.authorBataglioli, Rogerio Aparecidoen
dc.contributor.authorKaur, Harsimranen
dc.contributor.authorMuller, Johnen
dc.contributor.authorGeddes, Elizabethen
dc.contributor.authorChampine, Carrieen
dc.contributor.authorHsu, Bryan B.en
dc.date.accessioned2024-07-11T15:07:23Zen
dc.date.available2024-07-11T15:07:23Zen
dc.date.issued2024-07-10en
dc.description.abstractAdequately managing menstruation is an important factor in the overall quality of life for women. With a growing discussion of the global need for its improvement, it is clear that better management of menstruation can positively influence social, educational, and professional outcomes. Herein, we describe a biopolymer-based formulation that gels blood in a mechanism alternative to coagulation. We first tested several biopolymer mixtures with blood and quantified increases in viscosity, finding that high-molecular-weight alginate in combination with glycerol could rapidly absorb and gel blood. We then demonstrated that this powder could be deployed both as a traditional menstrual pad filler and as an additive to menstrual cups to reduce leakage and spillage, respectively. Finally, we include an antimicrobial polymer to impair the growth of Staphylococcus aureus, a bacterium associated with toxic shock syndrome. Collectively, our work describes a biodegradable formulation derived from renewable resources that can improve menstrual care.en
dc.description.sponsorshipFunding was provided to B.B.H. by award no. 208-03-22 from the Commonwealth Health Research Board of Virginia. Funding to the GlycoMIP was provided by the National Science Foundation Materials Innovation Platform through Cooperative Agreement DMR-1933525. Funding to R.A.B. was provided, in part, by the Postdoctoral Fellowship in Drug Delivery from the PhRMA Foundation.en
dc.description.versionAccepted versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1016/j.matt.2024.06.028en
dc.identifier.urihttps://hdl.handle.net/10919/120644en
dc.language.isoenen
dc.publisherCell Pressen
dc.subjectWomen's healthen
dc.subjectMensesen
dc.subjectPerioden
dc.subjectMenstruationen
dc.subjectmenorrhagiaen
dc.titleA naturally derived biomaterial formulation for improved menstrual careen
dc.title.serialMatteren
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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