Mechanisms of change in psychosocial interventions for autism spectrum disorders.

dc.contributor.authorLerner, M. D.en
dc.contributor.authorWhite, S. W.en
dc.contributor.authorMcPartland, J. C.en
dc.contributor.departmentPsychologyen
dc.coverage.spatialFranceen
dc.date.accessioned2016-10-12T15:07:54Zen
dc.date.available2016-10-12T15:07:54Zen
dc.date.issued2012-09en
dc.description.abstractResearch into psychosocial interventions (particularly cognitive-behavior therapies and social skills training) for social-communication deficits among individuals with autism spectrum disorder (ASD) has proliferated over the past decade. While this research has provided some empirical support for the efficacy of these interventions, little work has begun to elucidate therapeutic mechanisms-the when, why, how, for whom, and under what conditions an intervention may produce change, identification of mechanisms underlying these effects should help advance ASD intervention research. This article describes methods for assessing such mechanisms (ie, mediators and moderators) and presents promising candidates for common mechanisms impacting treatment response: behavior modification, therapeutic relationship, social knowledge, social motivation, social information processing, executive functioning, and internalizing comorbidities. Finally, future directions are discussed as a program of psychosocial intervention research designed to identify predictors of individual differences in treatment response (including biomarkers), isolate active therapeutic ingredients, and promote dissemination of optimized interventions.en
dc.description.versionPublished versionen
dc.format.extent307 - 318 page(s)en
dc.identifier.eissn1958-5969en
dc.identifier.issue3en
dc.identifier.urihttp://hdl.handle.net/10919/73199en
dc.identifier.volume14en
dc.languageengen
dc.relation.urihttp://www.ncbi.nlm.nih.gov/pubmed/23226955en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectallianceen
dc.subjectautism spectrum disorderen
dc.subjectbiomarkeren
dc.subjectcognitive-behavioral therapyen
dc.subjectinterventionen
dc.subjectmechanismen
dc.subjectmediatoren
dc.subjectmoderatoren
dc.subjectsocial knowledgeen
dc.subjectsocial skills trainingen
dc.subjectChilden
dc.subjectChild Development Disorders, Pervasiveen
dc.subjectChild, Preschoolen
dc.subjectCognitive Therapyen
dc.subjectHumansen
dc.subjectSocial Behavioren
dc.titleMechanisms of change in psychosocial interventions for autism spectrum disorders.en
dc.title.serialDialogues in Clinical Neuroscienceen
dc.typeArticle - Refereeden
dc.type.otherResearch Support, N.I.H., Extramuralen
dc.type.otherResearch Support, Non-U.S. Gov'ten
dc.type.otherReviewen
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Faculty of Health Sciencesen
pubs.organisational-group/Virginia Tech/Scienceen
pubs.organisational-group/Virginia Tech/Science/COS T&R Facultyen
pubs.organisational-group/Virginia Tech/Science/Psychologyen

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