Bokeelamides: Lipopeptides from Bacteria Associated with Marine Egg Masses

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dc.contributor.authorCampbell, Roseen
dc.contributor.authorKyei, Loisen
dc.contributor.authorPiedl, Karlaen
dc.contributor.authorZhang, Zheyeen
dc.contributor.authorChen, Mingen
dc.contributor.authorMevers, Emilyen
dc.date.accessioned2024-12-19T15:50:00Zen
dc.date.available2024-12-19T15:50:00Zen
dc.date.issued2024-11en
dc.description.abstractMoon snails (family: Naticidae) lay egg masses that are rich in bacterial species distinct from the surrounding environment. We hypothesized that this microbiome chemically defends the moon snail eggs from predation and pathogens. Herein, we report the discovery of bokeelamides, new lipopeptides from the egg mass-associated bacterium, Ectopseudomonas khazarica, which were discovered using mass spectrometry (MS)-based metabolomics. The structures of the bokeelamides were elucidated using two-dimensional (2D) nuclear magnetic resonance (NMR), tandem MS, Marfey’s, and genomic analyses.en
dc.description.versionPublished versionen
dc.format.extentPages 9693-9697en
dc.format.extent5 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1021/acs.orglett.4c03470en
dc.identifier.eissn1523-7052en
dc.identifier.issn1523-7060en
dc.identifier.issue45en
dc.identifier.orcidMevers, Emily [0000-0001-7986-5610]en
dc.identifier.pmid39486159en
dc.identifier.urihttps://hdl.handle.net/10919/123839en
dc.identifier.volume26en
dc.language.isoenen
dc.publisherAmerican Chemical Societyen
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/39486159en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subject.meshAnimalsen
dc.subject.meshSnailsen
dc.subject.meshMolecular Structureen
dc.subject.meshLipopeptidesen
dc.titleBokeelamides: Lipopeptides from Bacteria Associated with Marine Egg Massesen
dc.title.serialOrganic Lettersen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
pubs.organisational-groupVirginia Techen
pubs.organisational-groupVirginia Tech/Scienceen
pubs.organisational-groupVirginia Tech/Science/Chemistryen
pubs.organisational-groupVirginia Tech/Faculty of Health Sciencesen
pubs.organisational-groupVirginia Tech/All T&R Facultyen
pubs.organisational-groupVirginia Tech/Science/COS T&R Facultyen

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