The Clinical Pharmacology and Therapeutic Evaluation of Non-Steroidal Anti-Inflammatory Drugs in Adult Horses
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TR Number
Date
2023-05-10
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Abstract
This review firstly examines the underlying pathophysiology of pain and inflammation associated with orthopedic disease and endotoxemia. Then, it reviews the clinical pharmacology (pharmacokinetics and pharmacodynamics) of both conventional and non-conventional NSAIDs in the adult horse, and finally provides an overview of different modalities to evaluate the therapeutic efficacy of NSAIDs in research.
Description
Keywords
NSAIDs, horses, clinical pharmacology, endotoxemia, osteoarthritis
Citation
Mercer, M.A.; Davis, J.L.; McKenzie, H.C. The Clinical Pharmacology and Therapeutic Evaluation of Non-Steroidal Anti-Inflammatory Drugs in Adult Horses. Animals 2023, 13, 1597.