Biotribology: articular cartilage friction, wear, and lubrication

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dc.contributor.authorSchroeder, Matthew O.en
dc.contributor.committeechairFurey, Michael J.en
dc.contributor.committeememberEiss, Norman S. Jr.en
dc.contributor.committeememberViet, Hugo P.en
dc.contributor.departmentMechanical Engineeringen
dc.date.accessioned2014-03-14T21:52:47Zen
dc.date.adate2008-12-30en
dc.date.available2014-03-14T21:52:47Zen
dc.date.issued1995en
dc.date.rdate2008-12-30en
dc.date.sdate2008-12-30en
dc.description.abstractThis study developed, explored, and refined techniques for the in vitro study of cartilage-on-cartilage friction, deformation, and wear. Preliminary results of in vitro cartilage-on- cartilage experiments with emphasis on wear and biochemistry are presented. Cartilage-bone specimens were obtained from the stifle joints of steers from a separate controlled study. The load, sliding speed, and traverse of the lower specimens were held constant as lubricant and test length were varied. Lubricants tested consisted of a phosphate buffered saline solution, bovine serum, and bovine synovial fluid. Synovial fluid as a lubricant produced the least amount of damage to the cartilage. Serum produced more wear and damage than synovial fluid, but less than buffered saline (which produced the most damage). Three-hour tests produced more wear than one-hour tests, with severe damage to the lower plug in several of the three-hour tests. Analysis of the results was possible through: data acquisition of normal load, tangential load, and LVDT displacement; photomacrographs; ESEM and SEM surface studies; stained cross-sectional slides of cartilage; and hydroxyproline analysis of cartilage wear. Detailed procedures and discussion of results are presented along with recommended changes for future biotribology research.en
dc.description.degreeMaster of Scienceen
dc.format.extentxiv, 143 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-12302008-063639en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-12302008-063639/en
dc.identifier.urihttp://hdl.handle.net/10919/46457en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V855_1995.S376.pdfen
dc.relation.isformatofOCLC# 34408900en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectLubricantsen
dc.subjectjoint diseaseen
dc.subject.lccLD5655.V855 1995.S376en
dc.titleBiotribology: articular cartilage friction, wear, and lubricationen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineMechanical Engineeringen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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