JigCell Model Connector: Building Large Molecular Network Models from Components

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dc.contributor.authorJones, Thomas Carroll Jr.en
dc.contributor.committeechairShaffer, Clifford A.en
dc.contributor.committeechairTyson, John J.en
dc.contributor.committeememberHoops, Stefanen
dc.contributor.committeememberWatson, Layne T.en
dc.contributor.departmentComputer Scienceen
dc.date.accessioned2017-06-29T08:00:40Zen
dc.date.available2017-06-29T08:00:40Zen
dc.date.issued2017-06-28en
dc.description.abstractThe ever-growing size and complexity of molecular network models makes them difficult to construct and understand. Modifying a model that consists of tens of reactions is no easy task. Attempting the same on a model containing hundreds of reactions can seem nearly impossible. We present the JigCell Model Connector, a software tool that supports large-scale molecular network modeling. Our approach to developing large models is to combine together smaller models, making the result easier to comprehend. At the base, the smaller models (called modules) are defined by small collections of reactions. Modules connect together to form larger modules through clearly defined interfaces, called ports. In this work, we enhance the port concept by defining different types of ports. Not all modules connect together the same way, therefore multiple connection options need to exist.en
dc.description.degreeMaster of Scienceen
dc.format.mediumETDen
dc.identifier.othervt_gsexam:11726en
dc.identifier.urihttp://hdl.handle.net/10919/78277en
dc.publisherVirginia Techen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectComputational Systems Biologyen
dc.subjectHierarchical Model Compositionen
dc.subjectSBMLen
dc.subjectModeling Toolen
dc.subjectSoftwareen
dc.subjectJigCellen
dc.titleJigCell Model Connector: Building Large Molecular Network Models from Componentsen
dc.typeThesisen
thesis.degree.disciplineComputer Science and Applicationsen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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