Branched Peptide Boronic Acids (BPBAs): A Novel Mode of Binding Towards RNA

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dc.contributorChemistryen
dc.contributorCenter for Drug Discoveryen
dc.contributor.authorZhang, Wenyuen
dc.contributor.authorBryson, David I.en
dc.contributor.authorCrumpton, Jason B.en
dc.contributor.authorWynn, Jessica E.en
dc.contributor.authorSantos, Webster L.en
dc.contributor.departmentChemistryen
dc.date.accessed2015-04-17en
dc.date.accessioned2015-04-20T18:49:34Zen
dc.date.available2015-04-20T18:49:34Zen
dc.date.issued2013-02-07en
dc.description.abstractWe report branched peptideboronic acids (BPBAs) that bind to RRE IIB from an on-bead high-throughput screening of a 3.3.4-library (46 656 compounds). We demonstrate that boronic acids are tunable moieties that afford a novel binding mode towards RNA.en
dc.description.notesSupplementary information is included in a separate file - http://www.rsc.org/suppdata/cc/c3/c3cc00243h/c3cc00243h.pdfen
dc.description.sponsorshipNational Institutes of Health - RO1 GM093834en
dc.format.mimetypeapplication/pdfen
dc.identifier.citationZhang, W., Bryson, D. I., Crumpton, J. B., Wynn, J., & Santos, W. L. (2013). Branched peptideboronic acids (BPBAs): a novel mode of binding towards RNA. Chemical Communications, 49(24), 2436-2438. doi: 10.1039/C3CC00243Hen
dc.identifier.doihttps://doi.org/10.1039/C3CC00243Hen
dc.identifier.issn1359-7345en
dc.identifier.urihttp://hdl.handle.net/10919/51702en
dc.identifier.urlhttp://pubs.rsc.org/en/content/articlelanding/2013/cc/c3cc00243hen
dc.language.isoen_USen
dc.publisherThe Royal Society of Chemistryen
dc.rightsCreative Commons Attribution-NonCommercial 3.0 Unporteden
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/en
dc.subjectHIVen
dc.subjectAIDSen
dc.subjectRNAen
dc.subjectBoronic acid moietiesen
dc.subjectBranched peptide boronic acids (BPBAs)en
dc.titleBranched Peptide Boronic Acids (BPBAs): A Novel Mode of Binding Towards RNAen
dc.title.serialChemical Communicationsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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