Some metabolic effects of high oxygen concentrations in relation to retrolental fibroplasia

dc.contributor.authorSwartz, Jean Gibsonen
dc.contributor.departmentBiologyen
dc.date.accessioned2014-03-14T21:49:42Zen
dc.date.adate2013-11-15en
dc.date.available2014-03-14T21:49:42Zen
dc.date.issued1957en
dc.date.rdate2013-11-15en
dc.date.sdate2013-11-15en
dc.description.abstractNewborn rats and young guinea pigs have been exposed to high oxygen concentrations with subsequent analyses of ascorbic acid in liver and brain tissue. Newborn vats show a depletion of liver ascorbic acid only after exposure to 100% oxygen. Extending the exposure period in 70% oxygen did not result in any depletion. Brain ascorbic acid levels in newborn rats were depleted by exposure to both 100% and 70% oxygen until the 14th day of life. After that age, exposure failed to cause depletion. Guinea pigs identically exposed showed ascorbic acid depletion in both brain and liver tissue with the more marked depletion occurring in liver tissue. Abnormalities in the eyes of the experimental guinea pigs were demonstrated. Results of the tissue Vitamin A analyses are incomplete and inconclusive at this time.en
dc.description.degreeMaster of Scienceen
dc.format.extent46 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-11152013-040122en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-11152013-040122/en
dc.identifier.urihttp://hdl.handle.net/10919/45703en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V855_1957.S927.pdfen
dc.relation.isformatofOCLC# 25822552en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V855 1957.S927en
dc.subject.lcshRetrolental fibroplasiaen
dc.titleSome metabolic effects of high oxygen concentrations in relation to retrolental fibroplasiaen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineBiologyen
thesis.degree.grantorVirginia Polytechnic Instituteen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen
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