Cationic Polythiophenes as Responsive DNA-Binding Polymers

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dc.contributorVirginia Tech. Department of Chemistryen
dc.contributorAteneo de Manila University. Department of Chemistryen
dc.contributorXavier University - Ateneo de Cagayan University. Department of Chemistryen
dc.contributor.authorCarreon, Analyn C.en
dc.contributor.authorSantos, Webster L.en
dc.contributor.authorMatson, John B.en
dc.contributor.authorSo, Regina C.en
dc.contributor.departmentChemistryen
dc.date.accessed2015-04-17en
dc.date.accessioned2015-04-20T18:49:33Zen
dc.date.available2015-04-20T18:49:33Zen
dc.date.issued2013-09-23en
dc.description.abstractA new water soluble cationic polythiophene derivative, poly(N,N,N-trimethyl-3-(2-(thiophen-3-yl)acetamido)propan-1-aminium iodide), was synthesized via two consecutive post-polymerization functionalizations of poly(methyl 2-(thiophen-3-yl)acetate). This conjugated polymer binds DNA at N/P = 5 and forms polyplexes at N/P = 10. Its potential use as a theranostic gene delivery vehicle is investigated here.en
dc.description.notesSupplementary information is included in a separate fileen
dc.description.sponsorshipCommission on Higher Education, Philippines - PhD Sandwich Programen
dc.format.mimetypeapplication/pdfen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationCarreon, A. C., Santos, W. L., Matson, J. B., & So, R. C. (2014). Cationic polythiophenes as responsive DNA-binding polymers. Polymer Chemistry, 5(2), 314-317. doi: 10.1039/C3PY01069Den
dc.identifier.doihttps://doi.org/10.1039/C3PY01069Den
dc.identifier.issn1759-9954en
dc.identifier.urihttp://hdl.handle.net/10919/51694en
dc.identifier.urlhttp://pubs.rsc.org/en/content/articlelanding/2014/py/c3py01069den
dc.language.isoen_USen
dc.publisherThe Royal Society of Chemistryen
dc.rightsCreative Commons Attribution-NonCommercial 3.0 Unporteden
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/en
dc.subjectCationic polythiophenesen
dc.subjectGene delivery vectorsen
dc.subjectNanoparticlesen
dc.subjectConjugated polymersen
dc.titleCationic Polythiophenes as Responsive DNA-Binding Polymersen
dc.title.serialPolymer Chemistryen
dc.typeArticle - Refereeden
dc.typeDataseten
dc.type.dcmitypeTexten
dc.type.dcmitypeDataseten

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