Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program
| dc.contributor.author | Drager, Christopher John | en |
| dc.contributor.committeechair | Rankin, Janet L. Walberg | en |
| dc.contributor.committeemember | Newton, William E. | en |
| dc.contributor.committeemember | Williams, Jay H. | en |
| dc.contributor.department | Human Nutrition, Foods, and Exercise | en |
| dc.date.accessioned | 2013-02-19T22:40:58Z | en |
| dc.date.available | 2013-02-19T22:40:58Z | en |
| dc.date.issued | 2013-01-17 | en |
| dc.description.abstract | Aim: The purpose of this study was to investigate docosahexaenoic acid (DHA) ingestion on muscle damage and inflammation during the first two weeks of a novice resistance training (RT) program. Methods: This study was a placebo-controlled, double-blind design. Forty-one healthy untrained males between the ages of 18 and 28 years consumed 2,000 mg/d of either DHA or corn oil (PCB) for 44 days including a 28 day loading period. Serum fatty acids were analyzed to determine treatment efficacy. During the 17 day training period, an acute eccentric exercise bout was implemented followed by a full-body RT regimen thrice weekly. Six fasted blood draws (days 1, 2, 4, 7, 12, and 17) during this exercise period were analyzed for creatine kinase (CK) and C-reactive protein (CRP). Maximum isometric strength (ISO) of the elbow flexors, delayed onset muscle soreness (DOMS), and range of motion (ROM) were measured on day 1 prior to exercise and also on days 2, 3, 4, 7, 12, and 17. Results: The CK response and the area under the curve (AUC) analysis for DOMS trended to decrease in the DHA group in comparison to placebo (p=0.0925 and p=0.0536, respectively). Treatment showed no effect on CRP levels. DHA supplementation significantly increased serum DHA by 380% as a proportion of total fatty acids (p<0.0001). Conclusion: This study does not demonstrate convincing benefits of DHA ingestion to recovery from a new resistance exercise program but does suggest a need for further investigation. | en |
| dc.description.degree | Master of Science | en |
| dc.format.medium | ETD | en |
| dc.identifier.other | vt_gsexam:176 | en |
| dc.identifier.uri | http://hdl.handle.net/10919/19254 | en |
| dc.publisher | Virginia Tech | en |
| dc.rights | In Copyright | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en |
| dc.subject | Omega-3 fatty acids | en |
| dc.subject | strength training | en |
| dc.subject | creatine kinase | en |
| dc.subject | C-reactive protein | en |
| dc.title | Effect of DHA supplementation on muscle damage and inflammation during the first two weeks of a novice resistance training program | en |
| dc.type | Thesis | en |
| thesis.degree.discipline | Human Nutrition, Foods, and Exercise | en |
| thesis.degree.grantor | Virginia Polytechnic Institute and State University | en |
| thesis.degree.level | masters | en |
| thesis.degree.name | Master of Science | en |
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