MUSTN1 mRNA Abundance and Protein Localization is Greatest in Muscle Tissues of Chinese Meat-Quality Chickens

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dc.contributor.authorLi, Juanen
dc.contributor.authorChen, Yangen
dc.contributor.authorWang, Ya-Gangen
dc.contributor.authorZhao, Xiaolingen
dc.contributor.authorGilbert, Elizabeth R.en
dc.contributor.authorLiu, Yi-Pingen
dc.contributor.authorWang, Yanen
dc.contributor.authorHu, Yao-Dongen
dc.contributor.authorZhu, Qingen
dc.contributor.departmentAnimal and Poultry Sciencesen
dc.date.accessioned2017-09-20T18:18:57Zen
dc.date.available2017-09-20T18:18:57Zen
dc.date.issued2013-03-08en
dc.date.updated2017-09-20T18:18:57Zen
dc.description.abstractThe Mustang, Musculoskeletal Temporally Activated Novel-1 Gene (<i>MUSTN1</i>) plays an important role in regulating musculoskeletal development in mammals. We evaluated the developmental and tissue-specific regulation of MUSTN1 mRNA and protein abundance in Erlang Mountainous (EM) chickens. Results indicated that MUSTN1 mRNA/protein was expressed in most tissues with especially high expression in heart and skeletal muscle. The MUSTN1 protein localized to the nucleus in myocardium and skeletal muscle fibers. There were significant differences in mRNA and protein abundance among tissues, ages and between males and females. In conclusion, MUSTN1 was expressed the greatest in skeletal muscle where it localized to the nucleus. Thus, in chickens MUSTN1 may play a vital role in muscle development.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationLi, J.; Chen, Y.; Wang, Y.-G.; Zhao, X.-L.; Gilbert, E.R.; Liu, Y.-P.; Wang, Y.; Hu, Y.-D.; Zhu, Q. MUSTN1 mRNA Abundance and Protein Localization is Greatest in Muscle Tissues of Chinese Meat-Quality Chickens. Int. J. Mol. Sci. 2013, 14, 5545-5559.en
dc.identifier.doihttps://doi.org/10.3390/ijms14035545en
dc.identifier.urihttp://hdl.handle.net/10919/79180en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectErlang Mountainous chickensen
dc.subjectMUSTN1en
dc.subjectreal-time quantitative PCRen
dc.subjectskeletal muscleen
dc.subjectwestern blottingen
dc.titleMUSTN1 mRNA Abundance and Protein Localization is Greatest in Muscle Tissues of Chinese Meat-Quality Chickensen
dc.title.serialInternational Journal of Molecular Scienceen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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