Frontal Regulation of Blood Glucose Levels as a Function of Hostility

From a neuropsychological perspective, hostile men have displayed dysregulation of right cerebral systems as evidenced through an exaggerated sympathetic stress response, with cardiovascular reactivity for blood pressure and heart rate. Altered right cerebral functioning, with hostility and anger, has been demonstrated within functional cerebral systems to include auditory (Demaree & Harrison, 1997), visual (Harrison & Gorelczenko, 1990; Herridge, Harrison, Mollet, & Shenal, 2003), somatosensory (Herridge, Harrison, & Demaree, 1997; Rhodes, Harrison, & Demaree, 2002), motor (Demaree, Higgins, Williamson, & Harrison, 2002) and premotor systems (Williamson & Harrison, 2003). Each of these studies has demonstrated cardiovascular reactivity (blood pressure and heart rates measures) concurrently with altered sensory or motor functional correlates of the right hemisphere. However, the neuropsychological mechanisms and functional regulation for the mobilization of glucose have not been examined.