Physiological Responses in OSA Patients to Ramping Exercise After CPAP Treatment

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dc.contributor.authorShifflett, D. Edward Jr.en
dc.contributor.committeechairHerbert, William G.en
dc.contributor.committeememberGregg, John M.en
dc.contributor.committeememberZedalis, Donalden
dc.contributor.committeememberWard, Christopher W.en
dc.contributor.departmentHuman Nutrition, Foods, and Exerciseen
dc.date.accessioned2011-08-06T16:01:20Zen
dc.date.adate1998-06-05en
dc.date.available2011-08-06T16:01:20Zen
dc.date.issued1999-04-15en
dc.date.rdate1999-06-05en
dc.date.sdate1998-04-24en
dc.description.abstractContinuous positive airway pressure (CPAP) is the primary therapy administered for those afflicted with obstructive sleep apnea (OSA). We examined the effects of CPAP therapy on physiological variables during a ramped exercise. The five male, OSA patients had mean values and standard deviations for RDI=60.7 +/- 19.1, BMI=29.9 +/- 2.9, and age=56 +/- 16.1 yr. Subjects were examined before and after 4 wk of CPAP therapy. After 4 wk of CPAP therapy, patient responses to exercise showed a 17.6%, (p<0.05) improvement in rating of perceived exertion (RPE) at identical power outputs (60% of the individual's apparent functional capacity). Statistical significance was not attained (p>0.05) upon analysis of the following parameters at 60% of the individuals maximum workload although there was a trend showing a decrease in these variables: heart rate (6% improvement), VO2 (11.7% improvement) systolic blood pressure (4% improvement), and rate pressure product (8.6% improvement). This data shows that the decrease in RPE during 60% of the individual's maximum predicted HR reserve corresponded with an increase in sleep quality (mean increase of 40%, 3.2 units) as measured by the Pittsburgh Sleep Quality Index before and after 4 wk of CPAP therapy. It was concluded that the improvement in exercise tolerance could be attributed to the subjective feelings of improved sleep quality after 4 wk of CPAP therapy. Key Words: Obstructive sleep apnea---CPAP--- exercise---physiological responses.en
dc.description.degreeMaster of Scienceen
dc.format.mediumETDen
dc.identifier.otheretd-43098-1124en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-43098-1124en
dc.identifier.urihttp://hdl.handle.net/10919/9865en
dc.publisherVirginia Techen
dc.relation.haspartthesis.front.pdfen
dc.relation.haspartthesis.pdfen
dc.relation.haspartATHESIS.TITLE.PDFen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectObstructive sleep apneaen
dc.subjectExerciseen
dc.subjectphysiological responseen
dc.subjectCPAPen
dc.titlePhysiological Responses in OSA Patients to Ramping Exercise After CPAP Treatmenten
dc.typeThesisen
thesis.degree.disciplineHuman Nutrition, Foods, and Exerciseen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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