What does "staying well" after depression mean? Chronic low grade symptomatology after treatment for depression is common

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dc.contributor.authorStrege, Marlene V.en
dc.contributor.authorRichey, John A.en
dc.contributor.authorSiegle, Greg J.en
dc.date.accessioned2024-01-24T17:51:37Zen
dc.date.available2024-01-24T17:51:37Zen
dc.date.issued2022-08-24en
dc.description.abstractBackground: Persistent low grade depression symptoms are common and impairing in major depressive disorder (MDD) yet rarely reported in treatment follow-up studies (Judd et al., 1998a; Kennedy et al., 2004), suggesting that extant sustained remission rates may not reflect this important clinical feature. Furthermore, no long-term MDD treatment follow-up study has reported on quality of life ratings across functioning levels and years throughout the follow-up period, thus the severity, breadth, and persistence of functional impairment remain unclear. Accordingly, the current study evaluated the course of MDD with consideration of low grade depressive symptomatology and holistic features (e.g., quality of life). Methods: We report long-term (9–14 years) follow-up data from individuals with MDD (N = 37) who underwent either Cognitive Therapy (CBT) or a course of selective serotonin reuptake inhibitor (SSRI) treatment. Patients provided retrospective reports of depression symptoms and quality of life in the years following treatment. Results: Chronic depression symptoms (most often mild in severity) and decreased quality of life in multiple domains are frequent and suggest poorer sustained remission rates than previously observed in the literature. Limitations: Study limitations include small sample size recruited via convenience sampling methods. Conclusions: Findings support a conceptualization of depression recovery that entails persistent symptoms and vulnerabilities. Clinical recommendations are provided for discussing these features of depression recovery with patients.en
dc.description.versionAccepted versionen
dc.format.extentPages 228-235en
dc.format.extent8 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1016/j.jad.2022.08.075en
dc.identifier.eissn1573-2517en
dc.identifier.issn0165-0327en
dc.identifier.orcidRichey, John [0000-0003-3004-9561]en
dc.identifier.otherS0165-0327(22)00931-4 (PII)en
dc.identifier.pmid36029878en
dc.identifier.urihttps://hdl.handle.net/10919/117651en
dc.identifier.volume317en
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/36029878en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectDepressionen
dc.subjectTreatmenten
dc.subjectCognitive Behavior Therapyen
dc.subjectPharmacotherapyen
dc.subjectQuality of lifeen
dc.subject.meshHumansen
dc.subject.meshRetrospective Studiesen
dc.subject.meshFollow-Up Studiesen
dc.subject.meshDepressionen
dc.subject.meshDepressive Disorder, Majoren
dc.subject.meshQuality of Lifeen
dc.subject.meshSelective Serotonin Reuptake Inhibitorsen
dc.titleWhat does "staying well" after depression mean? Chronic low grade symptomatology after treatment for depression is commonen
dc.title.serialJournal of Affective Disordersen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
dcterms.dateAccepted2022-08-22en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Scienceen
pubs.organisational-group/Virginia Tech/Science/Psychologyen
pubs.organisational-group/Virginia Tech/Faculty of Health Sciencesen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Science/COS T&R Facultyen

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