The evaluation of crosslinked poly-4-vinylpyridine as a packing material for size exclusion chromatography

Abstract

Crosslinked poly-4-vinylpyridine (XPVP) has not previously been used as a size exclusion chromatographic packing material. This material appears attractive for the analysis of nitrogen containing polymers because of its basic nitrogen functionality, and desirable physical properties. Its use as such is investigated with probe compounds in several different mobile phases. Various methods of separation of the XPVP material by particle size are employed. In addition, four column packing techniques were examined.