Modelling Allee effects in a transgenic mosquito population during range expansion

dc.contributor.authorWalker, Melodyen
dc.contributor.committeechairChilds, Lauren M.en
dc.contributor.committeememberBorggaard, Jeffrey T.en
dc.contributor.committeememberBlackwood, Julie C.en
dc.contributor.departmentMathematicsen
dc.date.accessioned2018-06-21T08:00:28Zen
dc.date.available2018-06-21T08:00:28Zen
dc.date.issued2018-06-20en
dc.description.abstractMosquitoes are vectors for many diseases that cause significant mortality and morbidity across the globe such as malaria, dengue fever and Zika. As mosquito populations expand their range into new areas, they may undergo mate-finding Allee effects such that their ability to successfully reproduce becomes difficult at low population densities. With new technology, creating target specific gene modification may now be a viable method for mosquito population control. We develop a mathematical model to investigate the effects of releasing transgenic mosquitoes into newly established low-density mosquito populations. Our model consists of two life stages (aquatic and adult), which are further divided into three genetically distinct groups: heterogeneous and homogeneous transgenic alleles that cause female infertility and a homogeneous wild type. We perform analytical and numerical analyses on the equilibria to determine the level of saturation needed to eliminate mosquitoes in a given area. This model demonstrates the potential for a gene drive system to reduce the spread of invading mosquito populations.en
dc.description.degreeMaster of Scienceen
dc.format.mediumETDen
dc.identifier.othervt_gsexam:15565en
dc.identifier.urihttp://hdl.handle.net/10919/83598en
dc.publisherVirginia Techen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectmosquito dynamicsen
dc.subjectAllee effecten
dc.subjectgene driveen
dc.subjectmathematical modelen
dc.titleModelling Allee effects in a transgenic mosquito population during range expansionen
dc.typeThesisen
thesis.degree.disciplineMathematicsen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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