Identification of Anxiety Endophenotypes Using Multidimensional Measures of Attention

dc.contributor.authorStrege, Marlene Vernetteen
dc.contributor.committeechairRichey, John A.en
dc.contributor.committeememberOllendick, Thomas H.en
dc.contributor.committeememberBell, Martha Annen
dc.contributor.committeememberGracanin, Denisen
dc.contributor.departmentPsychologyen
dc.date.accessioned2017-06-13T19:43:39Zen
dc.date.adate2017-01-19en
dc.date.available2017-06-13T19:43:39Zen
dc.date.issued2016-11-30en
dc.date.rdate2017-01-19en
dc.date.sdate2016-12-14en
dc.description.abstractThe relationship between attention bias and anxiety has been robustly supported across paradigms and disorders; however, most published studies have ignored the known multidimensional nature of attention, and instead proceeded in measuring attention bias as a unitary construct, resulting in a lack of clarity regarding which attentional mechanisms contribute to specific manifestations of anxiety. In the current study we addressed this by collecting response latency data on three basic attentional processes, (1) attentional orienting, (2) attentional disengagement, and (3) attentional control to evaluate their relationship to specific anxiety symptoms. In a final sample of 149 college undergraduates, who either completed the computer tasks in-lab (N = 28) or online (N = 121), we used an unsupervised clustering approach (k-means clustering) to assign individual cases to clusters, depending upon their performance on measures of attention. We used a supervised machine learning approach (random forest), to cross-validate the unsupervised classification results. Anxiety symptoms were then set as predictors, predicting cluster membership using multinomial logistic regression. With the unsupervised k-means clustering approach, we found four clusters in the data. The random forest algorithm suggested variable prediction accuracy, dependent upon cluster size. Anxiety symptoms were unrelated to attention cluster membership. Study results were limited, which may be influenced by potential data collection and analytic factors.en
dc.description.degreeMaster of Scienceen
dc.identifier.otheretd-12142016-211106en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-12142016-211106/en
dc.identifier.urihttp://hdl.handle.net/10919/78059en
dc.language.isoen_USen
dc.publisherVirginia Techen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectattentionen
dc.subjectanxietyen
dc.titleIdentification of Anxiety Endophenotypes Using Multidimensional Measures of Attentionen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplinePsychologyen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen
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