Diet and Hygiene in Modulating Autoimmunity During the Pandemic Era

Simple item page
dc.contributor.authorAbdelhamid, Leilaen
dc.contributor.authorLuo, Xin M.en
dc.date.accessioned2022-08-22T13:47:29Zen
dc.date.available2022-08-22T13:47:29Zen
dc.date.issued2022-01-05en
dc.description.abstractThe immune system is an efficiently toned machinery that discriminates between friends and foes for achieving both host defense and homeostasis. Deviation of immune recognition from foreign to self and/or long-lasting inflammatory responses results in the breakdown of tolerance. Meanwhile, educating the immune system and developing immunological memory are crucial for mounting defensive immune responses while protecting against autoimmunity. Still to elucidate is how diverse environmental factors could shape autoimmunity. The emergence of a world pandemic such as SARS-CoV-2 (COVID-19) not only threatens the more vulnerable individuals including those with autoimmune conditions but also promotes an unprecedented shift in people's dietary approaches while urging for extraordinary hygiene measures that likely contribute to the development or exacerbation of autoimmunity. Thus, there is an urgent need to understand how environmental factors modulate systemic autoimmunity to better mitigate the incidence and or severity of COVID-19 among the more vulnerable populations. Here, we discuss the effects of diet (macronutrients and micronutrients) and hygiene (the use of disinfectants) on autoimmunity with a focus on systemic lupus erythematosus.en
dc.description.notesFunding Preparation of this manuscript was supported by the NIH/NIAMS under award number R01-AR073240en
dc.description.sponsorshipNIH/NIAMS [R01-AR073240]en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.3389/fimmu.2021.749774en
dc.identifier.issn1664-3224en
dc.identifier.other749774en
dc.identifier.pmid35069526en
dc.identifier.urihttp://hdl.handle.net/10919/111575en
dc.identifier.volume12en
dc.language.isoenen
dc.publisherFrontiersen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectdieten
dc.subjecthygieneen
dc.subjectimmunomodulationen
dc.subjectimmune homeostasisen
dc.subjectautoimmunityen
dc.subjectCOVID-19en
dc.titleDiet and Hygiene in Modulating Autoimmunity During the Pandemic Eraen
dc.title.serialFrontiers in Immunologyen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
fimmu-12-749774.pdf
Size:
1.08 MB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections

Scholarly Works, Biomedical Sciences and Pathobiology
Destination Area: Global Systems Science (GSS)
Open Access Subvention Fund Articles