Development of the Passive Perfusion Probe for Non-Invasive Blood Perfusion Measurement

Simple item page
dc.contributor.authorRicketts, Patricia Lynnen
dc.contributor.committeecochairDiller, Thomas E.en
dc.contributor.committeecochairScott, Elaine P.en
dc.contributor.committeememberLanz, Otto I.en
dc.contributor.departmentMechanical Engineeringen
dc.date.accessioned2014-03-14T20:37:31Zen
dc.date.adate2007-07-06en
dc.date.available2014-03-14T20:37:31Zen
dc.date.issued2007-05-03en
dc.date.rdate2010-10-27en
dc.date.sdate2007-05-18en
dc.description.abstractA non-invasive blood perfusion system has been developed and tested in a phantom tissue and an animal model. The system uses a small sensor with a laminated flat thermocouple to measure the heat transfer response to an arbitrary thermal event (convective or conductive) imposed on the tissue surface. Blood perfusion and contact resistance are estimated by comparing heat flux data with a mathematical model of the tissue. The perfusion system was evaluated for repeatability and sensitivity using both a phantom tissue test stand and exposed rat liver tests. Perfusion in the phantom tissue tests was varied by controlling the flow of water into the phantom tissue test section, and the perfusion in the exposed liver tests was varied by temporarily occluding blood flow through the portal vein. The phantom tissue tests indicated that the probe can be used to detect small changes in perfusion (0.009 ml/ml/s). The probe qualitatively tracked the changes in the perfusion of the liver model due to occlusion of the portal vein.en
dc.description.degreeMaster of Scienceen
dc.identifier.otheretd-05182007-144354en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-05182007-144354/en
dc.identifier.urihttp://hdl.handle.net/10919/32959en
dc.publisherVirginia Techen
dc.relation.haspartThesisPatriciaRicketts3.pdfen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectBlood Perfusionen
dc.subjectHeat Fluxen
dc.subjectPhantom Tissueen
dc.subjectParameter Estimationen
dc.titleDevelopment of the Passive Perfusion Probe for Non-Invasive Blood Perfusion Measurementen
dc.typeThesisen
thesis.degree.disciplineMechanical Engineeringen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ThesisPatriciaRicketts3.pdf
Size:
6.67 MB
Format:
Adobe Portable Document Format
Download

Collections

Masters Theses