Development, testing, and evaluation of the central-flow, double- leaflet heart valve

dc.contributor.authorHerbert, James Daleen
dc.contributor.departmentMechanical Engineeringen
dc.date.accessioned2023-04-20T14:53:51Zen
dc.date.available2023-04-20T14:53:51Zen
dc.date.issued1975en
dc.description.abstractA review of the literature revealed that 1) all prosthetic heart valves to date are plagued by certain problems, 2) all prosthetic valves in current clinical use are central-occlusion valves which do not effectively simulate natural valve action, and 3) the development of a true central-flow valve with the potential benefits of reduced pressure drop, turbulence, hemolysis, and thromboembolism could be a significant contribution. A central-flow, double-leaflet valve was developed. The wear, pressure drop, turbulence, and regurgitation associated with the new valve were evaluated. The wear test results indicated the need for additional testing using more wear resistant pin-bearing combinations. The flow tests revealed that the new valve with a 65 degree opening angle produced less pressure drop than other prostheses, but the new valve did not reduce turbulence as compared to other prostheses. In addition, the backflow and mean leak associated with the new valve were too high. Details of the testing procedures are presented and recommendations for future valve modifications and testing are included.en
dc.description.degreeM.S.en
dc.format.extentvii, 71 leavesen
dc.format.mimetypeapplication/pdfen
dc.identifier.urihttp://hdl.handle.net/10919/114716en
dc.language.isoenen
dc.publisherVirginia Polytechnic Institute and State Universityen
dc.relation.isformatofOCLC# 19334111en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V855 1975.H46en
dc.subject.lcshCardiovascular instruments, Implanted -- Design and constructionen
dc.subject.lcshHeart valve prosthesis -- Design and constructionen
dc.subject.lcshHeart valves -- Design and constructionen
dc.titleDevelopment, testing, and evaluation of the central-flow, double- leaflet heart valveen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineMechanical Engineeringen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameM.S.en

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