Diagnostic accuracy of a point-of-care test using voided urine samples for detection of bacteriuria in dogs with signs of lower urinary tract disease

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dc.contributor.authorGrant, David C.en
dc.contributor.authorNappier, Michael T.en
dc.contributor.authorCorrigan, Virginia Kieferen
dc.contributor.departmentSmall Animal Clinical Sciencesen
dc.date.accessioned2021-08-24T13:31:44Zen
dc.date.available2021-08-24T13:31:44Zen
dc.date.issued2021-02-01en
dc.date.updated2021-08-24T13:31:42Zen
dc.description.abstractBackground: Bacterial urine culture is recommended in dogs suspected of having urinary tract infection (UTI), but there is expense and delay in obtaining such results. Hypothesis/Objective: To determine the diagnostic performance of a rapid immunoassay (RIA) dipstick for detection of bacteriuria using voided urine from dogs with clinical signs of lower UTI. Animals: Twenty-four client-owned dogs. Methods: Voided urine was collected and the RIA performed within 30 minutes. Urine collected by cystocentesis was submitted for aerobic urine culture. McNemar's test and kappa coefficient were calculated to determine agreement between the 2 tests. Results: Nine of 21 dogs (43%) had UTI verified by aerobic urine culture. There was 1 false-negative and no false-positive RIA results. Sensitivity, specificity, positive predictive value, and negative predictive value of the RIA were 89%, 100%, 100%, and 92%, respectively. Conclusions and Clinical Importance: This RIA is promising for correctly identifying whether or not voided urine samples from dogs with lower urinary tract clinical signs have true bacteriuria in a rapid, inexpensive manner. Additional patients should be enrolled in a similar study to determine if diagnostic performance is robust in a large population.en
dc.description.versionPublished versionen
dc.format.extentPages 993-996en
dc.format.extent4 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.1111/jvim.16040en
dc.identifier.eissn1939-1676en
dc.identifier.issn0891-6640en
dc.identifier.issue2en
dc.identifier.orcidNappier, Michael [0000-0003-0373-3309]en
dc.identifier.orcidGrant, David [0000-0002-7279-380X]en
dc.identifier.pmid33527463 (pubmed)en
dc.identifier.urihttp://hdl.handle.net/10919/104696en
dc.identifier.volume35en
dc.language.isoenen
dc.publisherWileyen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000613615600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsCreative Commons Attribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectLife Sciences & Biomedicineen
dc.subjectVeterinary Sciencesen
dc.subjectbladderen
dc.subjectcystitisen
dc.subjectinfectionen
dc.subjecturinary tracten
dc.subjecturine cultureen
dc.subject0707 Veterinary Sciencesen
dc.subjectVeterinary Sciencesen
dc.subject.meshAnimalsen
dc.subject.meshDogsen
dc.subject.meshUrinary Tract Infectionsen
dc.subject.meshBacteriuriaen
dc.subject.meshDog Diseasesen
dc.subject.meshUrinalysisen
dc.subject.meshSensitivity and Specificityen
dc.subject.meshPoint-of-Care Testingen
dc.titleDiagnostic accuracy of a point-of-care test using voided urine samples for detection of bacteriuria in dogs with signs of lower urinary tract diseaseen
dc.title.serialJournal of Veterinary Internal Medicineen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
dcterms.dateAccepted2021-01-15en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Veterinary Medicineen
pubs.organisational-group/Virginia Tech/Veterinary Medicine/Small Animal Clinical Sciencesen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Veterinary Medicine/CVM T&R Facultyen
pubs.organisational-group/Virginia Tech/Graduate studentsen
pubs.organisational-group/Virginia Tech/Graduate students/Masters studentsen

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