Venous blood gas and chemistry components are moderately heritable in commercial white egg-laying hens under acute or chronic heat exposure

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dc.contributor.authorRowland, Kayleeen
dc.contributor.authorPersia, Michael E.en
dc.contributor.authorRothschild, Max F.en
dc.contributor.authorSchmidt, Carl J.en
dc.contributor.authorLamont, Susan J.en
dc.date.accessioned2021-10-13T13:14:41Zen
dc.date.available2021-10-13T13:14:41Zen
dc.date.issued2019-09-01en
dc.date.updated2021-10-13T13:14:39Zen
dc.description.abstractHeat stress has a large negative impact on poultry around the world in both intensive and small-scale production systems. Better understanding of genetic factors contributing to response to high ambient temperatures would provide a basis to develop strategies for alleviating negative impacts of heat on poultry production. The objective of this work was to characterize the genetic control (heritability estimate and quantitative trait loci (QTL)) of blood chemistry components before and after exposure to acute and chronic high ambient temperature in a commercial egg laying line Hy-Line W-36 female parent line mature hens were exposed to 4 wk of daily cyclic heat exposure. Blood was collected pre-heat, on the first day of heat, and 2 and 4 wk post heat initiation and analyzed immediately using an i-STAT® hand-held blood analyzer. Thirteen blood components were quantified at the 4 time points: pH, pCO2, pO2, HCO3, TCO2, sO2, iCa, Na, K, base excess, glucose, “hematocrit” (estimated from blood electrical conductivity, BEC), and “hemoglobin” (calculated from BEC). Heritabilities were estimated using genomic relationship information obtained from 600k SNP chip data. All 13 parameters exhibited a significant change after 5 h of heat exposure and most did not return to pre-heat levels throughout the duration of the study. Eight parameters (base excess, glucose, hemoglobin, HCO3, hematocrit, K, pCO2, TCO2) had heritability estimates differing from zero at one or more time points (0.21 to 0.45). The traits with significant heritability would be good candidates for use as biomarkers in a selection program if they are correlated with traits of economic importance that are more difficult to measure. QTL were identified for nine of the traits at one or more time point. These nine traits, however, did not have significant heritability estimates suggesting that while some QTL have been identified their effects are generally small.en
dc.description.versionPublished versionen
dc.format.extentPages 3426-3430en
dc.format.extent5 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.3382/ps/pez204en
dc.identifier.eissn1525-3171en
dc.identifier.issn0032-5791en
dc.identifier.issue9en
dc.identifier.otherS0032-5791(19)30633-9 (PII)en
dc.identifier.pmid31002114en
dc.identifier.urihttp://hdl.handle.net/10919/105284en
dc.identifier.volume98en
dc.language.isoenen
dc.publisherOxford University Pressen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000487004200008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectLife Sciences & Biomedicineen
dc.subjectAgriculture, Dairy & Animal Scienceen
dc.subjectAgricultureen
dc.subjectchronic heat stressen
dc.subjectacute heat stressen
dc.subjecti-STATR (R)en
dc.subjectGWASen
dc.subjectlaying henen
dc.subjectPORTABLE CLINICAL ANALYZERen
dc.subjectI-STATen
dc.subjectSTRESSen
dc.subjectCHICKENSen
dc.subjectIMPACTen
dc.subjecti-STAT®en
dc.subjectDairy & Animal Scienceen
dc.subject0605 Microbiologyen
dc.subject0702 Animal Productionen
dc.subject0908 Food Sciencesen
dc.subject.meshAnimalsen
dc.subject.meshChickensen
dc.subject.meshBlood Gas Analysisen
dc.subject.meshHeredityen
dc.subject.meshQuantitative Trait Locien
dc.subject.meshHot Temperatureen
dc.subject.meshStress, Physiologicalen
dc.titleVenous blood gas and chemistry components are moderately heritable in commercial white egg-laying hens under acute or chronic heat exposureen
dc.title.serialPoultry Scienceen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
dcterms.dateAccepted2019-03-21en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciencesen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Animal and Poultry Sciencesen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Facultyen

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