Evaluation of the microcirculation of the equine small intestine following intramural distention and reperfusion

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dc.contributor.authorDabareiner, Robin Marieen
dc.contributor.committeechairSullins, Kenneth E.en
dc.contributor.committeememberWhite, Nathaniel A. IIen
dc.contributor.committeememberSnyder, J. R.en
dc.contributor.committeememberPfeiffer, Carl J.en
dc.contributor.departmentVeterinary Medical Sciencesen
dc.date.accessioned2014-03-14T21:44:32Zen
dc.date.adate2009-09-05en
dc.date.available2014-03-14T21:44:32Zen
dc.date.issued1992-04-05en
dc.date.rdate2009-09-05en
dc.date.sdate2009-09-05en
dc.description.abstractThe effects of intraluminal distention (25 cm H₂O, 120 minutes) and subsequent decompression (60 minutes) on the intramural vascular patterns of the equine small intestine was evaluated in 7 anesthetized horses. The vascular system of experimental and control segments were injected with a blue-colored radiopaque medium for microangiography and histology or a diluted methyl methacrylate (MERCOX CL-2B) for scanning electron microscopy. The distended segments had shortened villi that were separated by expanded crypts and mesothelial cell loss, neutrophil infiltration and edema in the seromuscular layer. The number of filled vessels was decreased in the seromuscular layer and to a lesser extent in the mucosal layer in the distended segments compared to controls. Following reperfusion, the morphologic lesions progressed and the number of observed vessels increased in all layers; however the vascular density did not return to the pre distention state. This study identifies altered intramural vascular patterns in the equine jejunum during luminal distention and reperfusion.en
dc.description.degreeMaster of Scienceen
dc.format.extentvi, 111 leavesen
dc.format.mediumBTDen
dc.format.mimetypeapplication/pdfen
dc.identifier.otheretd-09052009-040410en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-09052009-040410/en
dc.identifier.urihttp://hdl.handle.net/10919/44550en
dc.language.isoenen
dc.publisherVirginia Techen
dc.relation.haspartLD5655.V855_1992.D322.pdfen
dc.relation.isformatofOCLC# 26187322en
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subject.lccLD5655.V855 1992.D322en
dc.subject.lcshHorses -- Physiologyen
dc.subject.lcshIntestine, Small -- Obstructionsen
dc.subject.lcshIntestine, Small -- Surgeryen
dc.subject.lcshMicrocirculationen
dc.titleEvaluation of the microcirculation of the equine small intestine following intramural distention and reperfusionen
dc.typeThesisen
dc.type.dcmitypeTexten
thesis.degree.disciplineVeterinary Medical Sciencesen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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