Exercise and Immunodeficiency Affect Immunoglobulins in Endurance Horses

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dc.contributor.authorKrick, Kari Elizabethen
dc.contributor.committeechairHoffman, Rhonda M.en
dc.contributor.committeecochairKronfeld, David S.en
dc.contributor.committeememberSplan, Rebecca K.en
dc.contributor.departmentAnimal and Poultry Sciencesen
dc.date.accessioned2014-03-14T21:41:30Zen
dc.date.adate2002-08-01en
dc.date.available2014-03-14T21:41:30Zen
dc.date.issued2002-07-16en
dc.date.rdate2003-08-01en
dc.date.sdate2002-07-29en
dc.description.abstractTwo studies were conducted on endurance horses predominantly of Arabian breeding participating in an 80 km ride dedicated to research in April 2001 (Trial 1) and April 2002 (Trial 2). Objectives were to determine effects of endurance exercise, antioxidant supplementation, and a feed rich in fiber and fat vs. a high fat sweet feed on immunoglobulin A and G concentrations as well as identify selective IgA deficiency in endurance horses of Arabian breeding. There were no effects of distance in Trial 1 on IgA (P = 0.73) or IgG (P = 0.18) concentrations. In Trial 2, IgA concentrations increased (P = 0.05) and IgG concentrations increased (P = 0.006) after the start of the race. There were no effects of antioxidant supplementation on IgA (P = 0.16), IgG (P = 0.16), and IgM (P = 0.70) concentrations. There were no diet effects on IgA (P = 0.80), IgG (P = 0.59), and IgM (P = 0.54) concentrations. There were horses in both trials that were deficient in IgA only. Concentrations of IgG and IgM were within normal ranges, and there were no differences in training, performance and transportation variables, IgG concentrations, antioxidant supplementation, and feed supplementation compared to the horses with normal IgA concentrations. The concentration of IgM was higher in IgA deficient horses in Trial 1 (P = 0.035) and Trial 2 (P = 0.017). Horses with deficient IgA tended to be associated with health problems commonly found in humans and dogs affected with selective IgA deficiency.en
dc.description.degreeMaster of Scienceen
dc.identifier.otheretd-07292002-143104en
dc.identifier.sourceurlhttp://scholar.lib.vt.edu/theses/available/etd-07292002-143104/en
dc.identifier.urihttp://hdl.handle.net/10919/43971en
dc.publisherVirginia Techen
dc.relation.haspartKrick.pdfen
dc.rightsIn Copyrighten
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en
dc.subjectExerciseen
dc.subjectHorsesen
dc.subjectimmunodeficiencyen
dc.subjectimmunoglobulinsen
dc.subjectimmunityen
dc.titleExercise and Immunodeficiency Affect Immunoglobulins in Endurance Horsesen
dc.typeThesisen
thesis.degree.disciplineAnimal and Poultry Sciencesen
thesis.degree.grantorVirginia Polytechnic Institute and State Universityen
thesis.degree.levelmastersen
thesis.degree.nameMaster of Scienceen

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