Complicated Post-Partum HELLP Syndrome Causing Acute Renal Failure and a Spontaneous Acute Subdural Hematoma

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dc.contributor.authorShah, Farhanen
dc.contributor.authorPatel, Nielen
dc.contributor.authorPatel, Brijesh B.en
dc.date.accessioned2024-03-06T20:04:10Zen
dc.date.available2024-03-06T20:04:10Zen
dc.date.issued2021-02-08en
dc.description.abstractHELLP syndrome is characterized by hemolysis, elevated liver enzymes, and thrombocytopenia. It is a devastating illness that typically occurs in the third trimester of gestation. We present a unique case of complicated post-partum HELLP syndrome. The patient was a 34-year-old Caucasian G1PO woman at 40 weeks' gestational age who presented for induction of labor. She underwent successful vaginal delivery. However, postoperatively the patient developed HELLP syndrome complicated by acute renal failure. She was transferred to the intensive care unit, where her renal function continued to decline, ultimately necessitating hemodialysis. She subsequently spontaneously developed an acute subdural hematoma. Most cases of HELLP syndrome occur in the third trimester, whereas fewer manifest post-partum. The pathophysiology of HELLP syndrome is poorly understood. While the defining organ of injury in HELLP syndrome is the liver, both kidney injury and spontaneous subdural hematomas can occur, as seen in this patient. The gold standard therapy for HELLP syndrome is prompt delivery of the fetus. HELLP syndrome continues to be a serious constellation of symptoms that can affect women late in their gestational period. As illustrated in this case report, prompt diagnosis of HELLP syndrome and appropriate management is critical.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.doihttps://doi.org/10.7759/cureus.13233en
dc.identifier.eissn2168-8184en
dc.identifier.issn2168-8184en
dc.identifier.issue2en
dc.identifier.orcidPatel, Brijesh [0000-0001-8593-749X]en
dc.identifier.otherPMC7947262en
dc.identifier.pmid33728182en
dc.identifier.urihttps://hdl.handle.net/10919/118290en
dc.identifier.volume13en
dc.language.isoenen
dc.publisherSpringeren
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/33728182en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectHELLPen
dc.subjecthemolysisen
dc.subjectacute subdural hemaotmaen
dc.subjectacute renal failure and hemodialysis in icuen
dc.subjectacute subdural hematomaen
dc.titleComplicated Post-Partum HELLP Syndrome Causing Acute Renal Failure and a Spontaneous Acute Subdural Hematomaen
dc.title.serialCureusen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dcterms.dateAccepted2021-01-29en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicineen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/Internal Medicineen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/Internal Medicine/Pulmonary/Sleep Medicineen
pubs.organisational-group/Virginia Tech/VT Carilion School of Medicine/TEACH Membersen

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