Faculty Works, Bradley Department of Electrical and Computer Engineering

Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-Source Data Integration

Zhang, Yuji; Xuan, Jianhua; de los Reyes, Benildo G.; Clarke, Robert; Ressom, Habtom W. (PLOS, 2010-04-21)

Background Precise regulation of the cell cycle is crucial to the growth and development of all organisms. Understanding the regulatory mechanism of the cell cycle is crucial to unraveling many complicated diseases, ...

Chemotaxis in Densely Populated Tissue Determines Germinal Center Anatomy and Cell Motility: A New Paradigm for the Development of Complex Tissues

Hawkins, Jared B.; Jones, Mark T.; Plassmann, Paul E.; Thorley-Lawson, David A. (PLOS, 2011-12-01)

Germinal centers (GCs) are complex dynamic structures that form within lymph nodes as an essential process in the humoral immune response. They represent a paradigm for studying the regulation of cell movement in the ...

Long-Term Decision on Wind Investment with Considering Different Load Ranges of Power Plant for Sustainable Electricity Energy Market

Valinejad, Jaber; Marzband, Mousa; Funsho Akorede, Mudathir; D Elliott, Ian; Godina, Radu; Matias, João Carlos de Oliveira; Pouresmaeil, Edris (MDPI, 2018-10-22)

The aim of this paper is to provide a bi-level model for the expansion planning on wind investment while considering different load ranges of power plants in power systems at a multi-stage horizon. Different technologies ...

Classifier for Activities with Variations

Younes, Rabih; Jones, Mark; Martin, Thomas L. (MDPI, 2018-10-18)

Most activity classifiers focus on recognizing application-specific activities that are mostly performed in a scripted manner, where there is very little room for variation within the activity. These classifiers are mainly ...

Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites

Thiaville, Michelle M.; Stoeck, Alexander; Chen, Li; Wu, Ren-Chin; Magnani, Luca; Oidtman, Jessica; Shih, Ie-Ming; Lupien, Mathieu; Wang, Tian-Li (PLOS, 2012-05-02)

PBX1 is a TALE homeodomain transcription factor involved in organogenesis and tumorigenesis. Although it has been shown that ovarian, breast, and melanoma cancer cells depend on PBX1 for cell growth and survival, the ...

Towards Omni-Tomography-Grand Fusion of Multiple Modalities for Simultaneous Interior Tomography

Wang, Ge; Zhang, Jie; Gao, Hao; Weir, Victor; Yu, Hengyong; Cong, Wenxiang; Xu, Xiaochen; Shen, Haiou; Bennett, James; Furth, Mark; Wang, Yue; Vannier, Michael (PLOS, 2012-06-29)

We recently elevated interior tomography from its origin in computed tomography (CT) to a general tomographic principle, and proved its validity for other tomographic modalities including SPECT, MRI, and others. Here we ...

TAGCNA: A Method to Identify Significant Consensus Events of Copy Number Alterations in Cancer

Yuan, Xiguo; Zhang, Junying; Yang, Liying; Zhang, Shengli; Chen, Baodi; Geng, Yaojun; Wang, Yue (PLOS, 2012-07-18)

Somatic copy number alteration (CNA) is a common phenomenon in cancer genome. Distinguishing significant consensus events (SCEs) from random background CNAs in a set of subjects has been proven to be a valuable tool to ...

Comparative Analysis of Methods for Identifying Recurrent Copy Number Alterations in Cancer

Yuan, Xiguo; Zhang, Junying; Zhang, Shengli; Yu, Guoqiang; Wang, Yue (PLOS, 2012-12-20)

Recurrent copy number alterations (CNAs) play an important role in cancer genesis. While a number of computational methods have been proposed for identifying such CNAs, their relative merits remain largely unknown in ...

Investment Incentives in Competitive Electricity Markets

Valinejad, Jaber; Barforoshi, Taghi; Marzband, Mousa; Pouresmaeil, Edris; Godina, Radu; P. S. Catalão, João (MDPI, 2018-10-18)

This paper presents the analysis of a novel framework of study and the impact of different market design criterion for the generation expansion planning (GEP) in competitive electricity market incentives, under variable ...

Dynamic, Nondestructive Imaging of a Bioengineered Vascular Graft Endothelium

Whited, Bryce M.; Hofmann, Matthias C.; Lu, Peng; Xu, Yong; Rylander, Christopher G.; Wang, Ge; Sapoznik, Etai; Criswell, Tracy; Lee, Sang Jin; Soker, Shay; Rylander, Marissa Nichole (PLOS, 2013-04-09)

Bioengineering of vascular grafts holds great potential to address the shortcomings associated with autologous and conventional synthetic vascular grafts used for small diameter grafting procedures. Lumen endothelialization ...

High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring

de Assis, Sonia; Wärri, Anni; Cruz, M. Idalia; Laja, Olusola; Tian, Ye; Zhang, Bai; Wang, Yue; Huang, Tim H. M.; Hilakivi-Clarke, Leena (Nature Publishing Group, 2012-01-01)

Environmental factors can influence one's susceptibility to cancer, but it is not clear whether such an influence extends beyond the directly exposed generations. Here, feeding pregnant rats with a high-fat diet or a hormone ...

Magnetoelectric quasi-(0-3) nanocomposite heterostructures

Li, Yanxi; Wang, Zhongchang; Yao, Jianjun; Yang, Tiannan; Wang, Zhiguang; Hu, Jia-Mian; Chen, Chunlin; Sun, Rong; Tian, Zhipeng; Li, Jiefang; Chen, Long-Qing; Viehland, Dwight D. (Nature Publishing Group, 2015-12-01)

Magnetoelectric composites of magnetic and ferroelectric components are promising for their use in applications such as information storage. Here, the authors find that magnetic quasiparticles embedded in a ferroelectric ...

Unsupervised Deconvolution of Dynamic Imaging Reveals Intratumor Vascular Heterogeneity and Repopulation Dynamics

Chen, Li; Choyke, Peter L.; Wang, Niya; Clarke, Robert; Bhujwalla, Zaver M.; Hillman, Elizabeth M. C.; Wang, Ge; Wang, Yue (PLOS, 2014-11-07)

With the existence of biologically distinctive malignant cells originated within the same tumor, intratumor functional heterogeneity is present in many cancers and is often manifested by the intermingled vascular compartments ...

Coexistence of filamentary and homogeneous resistive switching with memristive and meminductive memory effects in Al/MnO2/SS thin film metal–insulator–metal device

Kamble, Girish U; Shetake, Nitin P; Yadav, Suhas D; Teli, Aviraj M; Patil, Dipali S; Pawar, Sachin A; Karanjkar, Milind M; Patil, Pramod S; Shin, Jae C; Orlowski, Marius K; Kamat, Rajanish K; Dongale, Tukaram D (2018-09-19)

Abstract In the present investigation, we have experimentally demonstrated the coexistence of filamentary and homogeneous resistive switching mechanisms in single Al/MnO2/SS thin film metal–insulator–metal ...