Dynein-Inspired Multilane Exclusion Process with Open Boundary Conditions

dc.contributor.authorNandi, Riyaen
dc.contributor.authorTäuber, Uwe C.en
dc.contributor.authorPriyankaen
dc.date.accessioned2021-10-22T14:13:15Zen
dc.date.available2021-10-22T14:13:15Zen
dc.date.issued2021-10-14en
dc.date.updated2021-10-22T13:56:02Zen
dc.description.abstractMotivated by the sidewise motions of dynein motors shown in experiments, we use a variant of the exclusion process to model the multistep dynamics of dyneins on a cylinder with open ends. Due to the varied step sizes of the particles in a quasi-two-dimensional topology, we observe the emergence of a novel phase diagram depending on the various load conditions. Under high-load conditions, our numerical findings yield results similar to the TASEP model with the presence of all three standard TASEP phases, namely the low-density (LD), high-density (HD), and maximal-current (MC) phases. However, for medium- to low-load conditions, for all chosen influx and outflux rates, we only observe the LD and HD phases, and the maximal-current phase disappears. Further, we also measure the dynamics for a single dynein particle which is logarithmically slower than a TASEP particle with a shorter waiting time. Our results also confirm experimental observations of the dwell time distribution: The dwell time distribution for dyneins is exponential in less crowded conditions, whereas a double exponential emerges under overcrowded conditions.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationNandi, R.; Täuber, U.C.; Priyanka. Dynein-Inspired Multilane Exclusion Process with Open Boundary Conditions. Entropy 2021, 23, 1343.en
dc.identifier.doihttps://doi.org/10.3390/e23101343en
dc.identifier.urihttp://hdl.handle.net/10919/105638en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectdynein motorsen
dc.subjectexclusion processen
dc.subjectphase diagramen
dc.subjectdwell time distributionen
dc.titleDynein-Inspired Multilane Exclusion Process with Open Boundary Conditionsen
dc.title.serialEntropyen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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