Structural divergence of chromosomes between malaria vectors Anopheles lesteri and Anopheles sinensis

Simple item page
dc.contributor.authorLiang, Jiangtaoen
dc.contributor.authorCheng, Biaoen
dc.contributor.authorZhu, Guodingen
dc.contributor.authorWei, Yunen
dc.contributor.authorTang, Jianxiaen
dc.contributor.authorCao, Junen
dc.contributor.authorMa, Yajunen
dc.contributor.authorSharakhova, Maria V.en
dc.contributor.authorXia, Aien
dc.contributor.authorSharakhov, Igor V.en
dc.contributor.departmentEntomologyen
dc.contributor.departmentFralin Life Sciences Instituteen
dc.date.accessioned2017-01-05T00:10:30Zen
dc.date.available2017-01-05T00:10:30Zen
dc.date.issued2016-11-25en
dc.description.abstractBackground Anopheles lesteri and Anopheles sinensis are two major malaria vectors in China and Southeast Asia. They are dramatically different in terms of geographical distribution, host preference, resting habitats, and other traits associated with ecological adaptation and malaria transmission. Both species belong to the Anopheles hyrcanus group, but the extent of genetic differences between them is not well understood. To provide an effective way to differentiate between species and to find useful markers for population genetics studies, we performed a comparative cytogenetic analysis of these two malaria vectors. Results Presented here is a standard cytogenetic map for An. lesteri, and a comparative analysis of chromosome structure and gene order between An. lesteri and An. sinensis. Our results demonstrate that much of the gene order on chromosomes X and 2 was reshuffled between the two species. However, the banding pattern and the gene order on chromosome 3 appeared to be conserved. We also found two new polymorphic inversions, 2Lc and 3Rb, in An. lesteri, and we mapped the breakpoints of these two inversions on polytene chromosomes. Conclusions Our results demonstrate the extent of structural divergence of chromosomes between An. lesteri and An. sinensis, and provide a new taxonomic cytogenetic tool to distinguish between these two species. Polymorphic inversions of An. lesteri could serve as markers for studies of the population structure and ecological adaptations of this major malaria vector.en
dc.description.versionPublished versionen
dc.format.extent? - ? (10) page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifier.citationParasites & Vectors. 2016 Nov 25;9(1):608en
dc.identifier.doihttps://doi.org/10.1186/s13071-016-1855-0en
dc.identifier.issn1756-3305en
dc.identifier.urihttp://hdl.handle.net/10919/73948en
dc.identifier.volume9en
dc.language.isoenen
dc.publisherBiomed Centralen
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000388533000009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.holderThe Author(s)en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectParasitologyen
dc.subjectCytogenetic mapen
dc.subjectChromosomal inversionsen
dc.subjectAnopheles lesterien
dc.subjectAnopheles sinensisen
dc.subjectGene orderen
dc.subjectArm homologyen
dc.subjectPolytene chromosomesen
dc.subjectHYRCANUS GROUPen
dc.subjectCULICIDAEen
dc.subjectDIPTERAen
dc.subjectCHINAen
dc.subjectSEQUENCESen
dc.subjectPHOTOMAPen
dc.subjectGAMBIAEen
dc.titleStructural divergence of chromosomes between malaria vectors Anopheles lesteri and Anopheles sinensisen
dc.title.serialParasites & Vectorsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciencesen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Facultyen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Entomologyen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Faculty of Health Sciencesen
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Structural divergence of chromosomes between malaria vectors Anopheles lesteri and Anopheles sinensis.pdf
Size:
2.15 MB
Format:
Adobe Portable Document Format
Description:
Publisher's Version
Download
License bundle
Now showing 1 - 1 of 1
Name:
VTUL_Distribution_License_2016_05_09.pdf
Size:
18.09 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
All Faculty Deposits
Journal Articles, BioMed Central and SpringerOpen
Scholarly Works, Entomology
Scholarly Works, Fralin Life Sciences Institute