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Orthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variants

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dc.contributor.authorWang, Boen
dc.contributor.authorHarms, Dominiken
dc.contributor.authorYang, Xing-Louen
dc.contributor.authorBock, C.-Thomasen
dc.date.accessioned2020-03-02T13:30:45Zen
dc.date.available2020-03-02T13:30:45Zen
dc.date.issued2020-02-25en
dc.date.updated2020-03-02T12:42:10Zen
dc.description.abstractHepatitis E virus (HEV) is an emerging zoonotic pathogen that has received an increasing amount of attention from virologists, clinicians, veterinarians, and epidemiologists over the past decade. The host range and animal reservoirs of HEV are rapidly expanding and a plethora of emerging HEV variants have been recently identified, some of which have the potential for interspecies infection. In this review, the detection of genetically diverse HEV variants, classified into and presumably associated with the species <i>Orthohepevirus</i> C, currently comprising HEV genotypes C1 and C2, by either serological or molecular approach is summarized. The distribution, genomic variability, and evolution of <i>Orthohepevirus</i> C are analyzed. Moreover, the potential risk of cross-species infection and zoonotic transmission of <i>Orthohepevirus</i> C are discussed.en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationWang, B.; Harms, D.; Yang, X.-L.; Bock, C.-T. Orthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variants. Pathogens 2020, 9, 154.en
dc.identifier.doihttps://doi.org/10.3390/pathogens9030154en
dc.identifier.urihttp://hdl.handle.net/10919/97109en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectOrthohepevirus Cen
dc.subjecthepatitis E virusen
dc.subjectgenetic variabilityen
dc.subjectmolecular evolutionen
dc.subjecthosten
dc.subjectzoonosisen
dc.titleOrthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variantsen
dc.title.serialPathogensen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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