Analysis of a membrane type blood oxygenator and a ventricle type blood pump

TR Number
Journal Title
Journal ISSN
Volume Title
Virginia Polytechnic Institute and State University

This study presented the development and in vitro analysis of the Arp Hembrane Type Blood Oxygenator and a ventricle type blood pump. The system is designed for newborns suffering from Respiratory Distress Syndrome (R.D.S.), especially the 15% who are unable to be helped by the Arp Infant Respirator.

The analysis included oxygen transfer studies and hemolysis studies. The oxygenator was able to transfer as much as 140cc0₂/min/m² at a flow rate of 300 ml/min with flow augmentation. Inlet oxygen saturation 1vas between 25-35%.

Both the oxygenator and the ventricle type blood pump caused only very low levels of hemolysis. The pump showed a net increase of 54 mg hemoglobin/100 ml plasma after 5 days of continuous running at a flow rate of 200 ml/min. The complete extracorporeal circuit showed a net increase of only 61 mg hemoglobin/100 ml plasma.

From this study, it is believed that this extracorporeal circuit can ,supply oxygen (140 cc0₂/min/m²) to a patient over an extended period of total or partial cardiopulmonary by-pass (at least 5 days) without significant levels of hemolysis (61 mg% after 5 days).