Research Note: Intestinal morphology and gene expression changes in broilers supplemented with lysolecithin

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dc.contributor.authorCloft, Sara E.en
dc.contributor.authorJia, Meitingen
dc.contributor.authorWong, Eric A.en
dc.contributor.departmentAnimal and Poultry Sciencesen
dc.date.accessioned2021-08-04T19:11:22Zen
dc.date.available2021-08-04T19:11:22Zen
dc.date.issued2021-07-01en
dc.date.updated2021-08-04T19:11:20Zen
dc.description.abstractLysolecithin is used as a feed additive to aid fat digestion and absorption in broiler chickens. Previous research has shown that dietary fat source influences how broilers respond to lysolecithin supplementation. Therefore, the objective of this study was to investigate the effect of lysolecithin on a diet formulated with soybean oil on jejunum morphology and expression of selected genes in broiler chickens. Male Cobb 500 chickens were fed a Control diet or the Control diet supplemented with lysolecithin (TRT) from day of hatch to day 28. Jejunal samples were collected at day 10 for morphological and gene expression analysis. Feeding the TRT diet did not affect BW, villus height (VH), crypt depth (CD) or VH/CD ratio compared to Control fed chickens. Differential gene expression in the jejunum was analyzed using a custom microarray. Using a t test, 36 genes were found to be upregulated in TRT fed chickens compared to chickens fed the Control diet. The two most upregulated genes were carbonic anhydrase VII and interleukin 8-like 2, which are associated with healthy intestines. In summary, lysolecithin supplementation in a diet formulated with soybean oil caused no morphological changes but upregulated a number of genes in the jejunum.en
dc.description.versionPublished versionen
dc.format.extent4 page(s)en
dc.format.mimetypeapplication/pdfen
dc.identifierARTN 101192 (Article number)en
dc.identifier.doihttps://doi.org/10.1016/j.psj.2021.101192en
dc.identifier.eissn1525-3171en
dc.identifier.issn0032-5791en
dc.identifier.issue7en
dc.identifier.orcidWong, Eric [0000-0002-1891-5466]en
dc.identifier.otherS0032-5791(21)00226-1 (PII)en
dc.identifier.pmid34089931 (pubmed)en
dc.identifier.urihttp://hdl.handle.net/10919/104577en
dc.identifier.volume100en
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urihttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000668228100016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=930d57c9ac61a043676db62af60056c1en
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectLife Sciences & Biomedicineen
dc.subjectAgriculture, Dairy & Animal Scienceen
dc.subjectAgricultureen
dc.subjectsoybean oilen
dc.subjectlysolecithinen
dc.subjectjejunumen
dc.subjectgene expressionen
dc.subjectbroiler chickensen
dc.subjectGASTROINTESTINAL-TRACTen
dc.subjectFATen
dc.subject0605 Microbiologyen
dc.subject0702 Animal Productionen
dc.subject0908 Food Sciencesen
dc.subjectDairy & Animal Scienceen
dc.subject.meshIntestinesen
dc.subject.meshAnimalsen
dc.subject.meshChickensen
dc.subject.meshLysophosphatidylcholinesen
dc.subject.meshDieten
dc.subject.meshGene Expressionen
dc.subject.meshAnimal Feeden
dc.subject.meshDietary Supplementsen
dc.subject.meshMaleen
dc.subject.meshAnimal Nutritional Physiological Phenomenaen
dc.titleResearch Note: Intestinal morphology and gene expression changes in broilers supplemented with lysolecithinen
dc.title.serialPoultry Scienceen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten
dc.type.otherArticleen
dc.type.otherJournalen
dcterms.dateAccepted2021-04-05en
pubs.organisational-group/Virginia Techen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciencesen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/Animal and Poultry Sciencesen
pubs.organisational-group/Virginia Tech/All T&R Facultyen
pubs.organisational-group/Virginia Tech/Agriculture & Life Sciences/CALS T&R Facultyen

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