The Development of Cytogenetic Maps for Malaria Mosquitoes

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dc.contributor.authorArtemov, Gleb N.en
dc.contributor.authorStegniy, Vladimir N.en
dc.contributor.authorSharakhova, Maria V.en
dc.contributor.authorSharakhov, Igor V.en
dc.contributor.departmentEntomologyen
dc.contributor.departmentFralin Life Sciences Instituteen
dc.date.accessioned2018-09-21T16:41:06Zen
dc.date.available2018-09-21T16:41:06Zen
dc.date.issued2018-09-17en
dc.date.updated2018-09-21T07:12:18Zen
dc.description.abstractAnopheline mosquitoes are important vectors of human malaria. Next-generation sequencing opens new opportunities for studies of mosquito genomes to uncover the genetic basis of a <i>Plasmodium</i> transmission. Physical mapping of genome sequences to polytene chromosomes significantly improves reference assemblies. High-resolution cytogenetic maps are essential for anchoring genome sequences to chromosomes as well as for studying breakpoints of chromosome rearrangements and chromatin protein localization. Here we describe a detailed pipeline for the development of high-resolution cytogenetic maps using polytene chromosomes of malaria mosquitoes. We apply this workflow to the refinement of the cytogenetic map developed for <i>Anopheles beklemishevi.</i>en
dc.description.versionPublished versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationArtemov, G.N.; Stegniy, V.N.; Sharakhova, M.V.; Sharakhov, I.V. The Development of Cytogenetic Maps for Malaria Mosquitoes. Insects 2018, 9, 121.en
dc.identifier.doihttps://doi.org/10.3390/insects9030121en
dc.identifier.urihttp://hdl.handle.net/10919/85070en
dc.language.isoenen
dc.publisherMDPIen
dc.rightsCreative Commons Attribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectcytogenetic mapen
dc.subjectchromosome mapen
dc.subjectmalaria mosquitoesen
dc.subjectAnophelesen
dc.subjectpolytene chromosomesen
dc.subjectAnopheles beklemishevien
dc.subjectchromosome map developmenten
dc.subjectphotomapen
dc.subjecthigh-pressure techniqueen
dc.subjectchromosome straighteningen
dc.titleThe Development of Cytogenetic Maps for Malaria Mosquitoesen
dc.title.serialInsectsen
dc.typeArticle - Refereeden
dc.type.dcmitypeTexten

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Journal Articles, Multidisciplinary Digital Publishing Institute (MDPI)
Scholarly Works, Entomology
Scholarly Works, Fralin Life Sciences Institute