Nanosensing of Hepatitis E Virus in Swine Using Graphene

Abstract

Sensing of the hepatitis E virus is crucial for effective porcine health management and prevention of spread to humans. This study presents the development of a nanosensor using graphene nanosheets to detect hepatitis E antigen within a minute. The graphene layer not only increases the loading of antibodies specific to the hepatitis E virus but also enhances sensitivity and selectivity. This sensor is sensitive to 10 fM of hepatitis E antigen. This nanosensor holds significant potential for the rapid and early detection and monitoring of hepatitis E, thereby contributing to enhanced public health outcomes and the safety of pork products.